[Bleeding from duodenal invasion of hepatocellulcar carcinoma]

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Direct invasion of the duodenum by HCC is rare. Sometimes it may cause a severe GI bleeding. In a prospective study from Hong Kong, 26 of the 55 HCC patients (47%) who presented with GI hemorrhage had bleeding from varices. Peptic ulceration was the second most common cause. Direct tumor invasion into the GI tract was found in only three patients. All three patients had tumors invading the duodenum.