[Why most published research findings are false]
ÃÖ±Ù ¹«Ã´ Èï¹Ì·Î¿î ³í¹®À» Àоú½À´Ï´Ù. Á¦¸ñÀº Why most published research findings are false. ±×¸®½ºÀÎ ¿ªÇÐÀÚ(epidemiologist)°¡ ¾´ À¯ÀÍÇÑ ±ÛÀ̾ú½À´Ï´Ù. ÀÌ·± ¹®ÀåÀÌ ³ª¿É´Ï´Ù. Claimed research findings may often be simply accurate measures of the prevailing bias. "È°ÀÚÈµÈ °ÍÀº Áø½Çº¸´Ù °ÅÁþÀÌ ¸¹´Ù"´Â Á¦ Æò¼Ò »ý°¢°ú ´Ù¸£Áö ¾Ê¾Æ ¹Ý°¡¿ï µû¸§ÀÔ´Ï´Ù.
¿µ±¹À̳ª ¹Ì±¹ÀÇ ÇÐÀÚµéÀÌ Á¤¸éÀ¸·Î evidence-based medicine (EBM)¿¡ ¹Ý´ëÇÏ´Â ±ÛÀ» ¾²±â´Â ¾î·Á¿ï °ÍÀÔ´Ï´Ù. ÁÖ·ù¿Í´Â °Å¸®°¡ ¸Õ ±×¸®½º¿¡¼ ÀÏÇÏ´Â ÇÐÀÚÀ̹ǷΠ¿ÀÈ÷·Á Áø½Ç¿¡ °¡±î¿î ±ÛÀ» ¾µ ¼ö ÀÖ¾ú°ÚÁö¿ä. »ç½Ç Àú´Â EBMÀ» º°·Î ¹ÏÁö ¾Ê½À´Ï´Ù. ÀÇÇп¡¼ evidence¶ó´Â °ÍÀÇ òõÀÌ ¿ö³« ³·±â ¶§¹®ÀÔ´Ï´Ù. ±×³ª¸¶ ³´´Ù´Â prospective randomized controlled trialÀ̶ó´Â °Í ÀÚü°¡ ±×´ÙÁö ¹ÏÀ»¸¸ÇÑ °ÍÀÌ ¸øµË´Ï´Ù. ÁÖÁ¦ÀÇ ¼±ÅúÎÅÍ µ¥ÀÌŸÀÇ Çؼ®±îÁö ¸¹Àº °úÁ¤¿¡¼ °´°ü¼ºÀ» ÀÒÀ» ¼ö ÀÖ´Â ºÎºÐÀÌ ³Ê¹« ¸¹´Ù°í º¾´Ï´Ù. ÀÌ·ÐÀº ±×·²½ÎÇÏÁö¸¸ ½ÇÁ¦ ¿¬±¸°¡ ÁøÇàµÇ´Â °ÍÀ» ¿·¿¡¼ ÁöÄѺ¸¸é..... ¸ÀÀÌ È® °©´Ï´Ù. Â÷¶ó¸® ³ôÀº µµ´ö¼ºÀ» °¡Áø Àü¹®°¡ÀÇ ÁÖ°üÀûÀÎ ´À³¦ÀÌ ´õ Áø½Ç¿¡ °¡±î¿ï ¶§°¡ ÀÖ½À´Ï´Ù.
ÀÌ·± Á¦¸ñÀÇ ³í¹®µµ ÀÖ¾ú½À´Ï´Ù. Why most biomedical findings echoed by newspapers turn out to be false: the case of attention deficit hyperactivity disorder. ºñ½ÁÇÑ ±ÛÀº ¾ÆÁÖ ¸¹½À´Ï´Ù. ÇÐȸ¿¡¼ ¹ßÇ¥ÇÑ ³»¿ë°ú ³í¹®ÀÌ ´Ù¸¥ °á°ú¸¦ º¸¿©ÁØ ¿¹µµ ÀûÁö ¾Ê½À´Ï´Ù (link).
ÃÖ±Ù ¾Æ·¡¿Í °°Àº ±â»çµµ ÀÖ¾ú½À´Ï´Ù. ´©±¸ ¸»ÀÌ Áø½ÇÀϱî¿ä? ƯÁ¾À» ¹Ù¶ó´Â ±âÀÚÀÇ ¸»ÀÌ Áø½ÇÀϱî¿ä? ±×·²½ÎÇÑ ¿¬±¸ ¾÷ÀûÀ» ¹Ù¶ó´Â ±³¼öÀÇ ¸»ÀÌ Áø½ÇÀϱî¿ä? Àú´Â ±¹¸³´ëÇÑ ¿¬±¸Áø½Ç¼ºÀ§¿øȸÀÇ °á·ÐÀ» ¹Ï´Â ¼ö ¹Û¿¡ ¾ø´Ù°í º¾´Ï´Ù. ÀÌ ¶ÇÇÑ ¹Ù²ð ¼ö ÀÖÀ¸³ª ±×³ª¸¶ ÇöÀç·Î¼´Â ÃÖ¼±À̴ϱî...
ÀÇÇÐ ¿¬±¸ÀÇ ºÒÆíÇÑ Áø½ÇÀ» º¸¿©ÁÖ´Â ¸¹Àº Ã¥ Áß¿¡¼ ¾Æ·¡ Ã¥Àº ´Ü¿¬ ¾Ð±ÇÀÔ´Ï´Ù. New England Journal of MedicineÀÇ ÆíÁýÀÚ¸¦ Áö³½ ºÐÀÌ ¾´ Ã¥ÀÔ´Ï´Ù.
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