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[20110202. Chromoendoscopy (13) - Methylene blue]

Methylene blue´Â methylthionine chloride ¿ë¾×À» ÁöĪÇÏ´Â ¿ë¾îÀÔ´Ï´Ù. º¸Åë 0.5-1 % ¿ë¾×À» ºÐ¹«ÇÏ°í 1-2ºÐ ±â´Ù¸° ÈÄ ¹°·Î ¾Ä°í °üÂûÇÕ´Ï´Ù. ±×·¯¸é intestinal metaplasia ºÎÀ§°¡ Ǫ¸¥»öÀ¸·Î ¿°»öµË´Ï´Ù. ƯÀÌÇÏ°Ôµµ gastric metaplasia´Â ¿°»öµÇÁö ¾Ê½À´Ï´Ù.

Methylene blue¸¦ ´Ù·® »ç¿ëÇÏ¸é ¼Òº¯À̳ª ´ëº¯ÀÌ Çª¸¥ »öÀ¸·Î º¯ÇÒ ¼ö ÀÖÀ¸¹Ç·Î ³î¶óÁö ¸¶½Ê½Ã¿À.

¾Æ·¡ »çÁøÀº intestinal metaplasia¿¡ methylene blue¸¦ »Ñ¸° ÈÄ º¯È­¸¦ º¸¿©ÁÖ°í ÀÖ½À´Ï´Ù (¹°·Ð Àá½Ã ±â´Ù¸° ÈÄ ¹°·Î ¾Ä¾ú½À´Ï´Ù). ±×·¯³ª ½ÇÁ¦ ÀÓ»ó¿¡¼­ intestinal metaplasia¸¦ È®ÀÎÇϱâ À§ÇÏ¿© methylene blue¸¦ »ç¿ëÇÒ ÇÊ¿ä´Â ¾ø´Ù°í º¾´Ï´Ù. (1) White light endoscopy¸¦ ÀÌ¿ëÇصµ ÃæºÐÈ÷ °üÂûÇÒ ¼ö Àֱ⠶§¹®ÀÔ´Ï´Ù. (2) Metaplastic gastritis·Î Áø´ÜÇѵé (°£È¤ °ËÁø °£°ÝÀ» Á¶ÀýÇÏ´Â °Í ÀÌ¿Ü¿¡) Ưº°È÷ ´Þ¶óÁö´Â °Íµµ ¾ø±â ¶§¹®ÀÔ´Ï´Ù.

ÃÖ±Ù Àú´Â methylene blue¸¦ °ÅÀÇ »ç¿ëÇÏÁö ¾Ê°í ÀÖ½À´Ï´Ù. ¹°·Ð ±³°ú¼­¿¡¼­´Â ¹Ù·¿½Äµµ¿¡¼­ methylene blue°¡ À¯¿ëÇÏ´Ù°í µÇ¾î ÀÖ½À´Ï´Ù. ±×·¯³ª Á¦°¡ °æÇèÇÑ ¹Ù·¿½ÄµµµéÀº white light endoscopy·Î ÃæºÐÈ÷ Àß º¸¿´À¸¸ç, NBI¸¦ ¾²¸é ´õÇÒ ³ªÀ§ ¾øÀÌ ¸íÈ®ÇØÁ³½À´Ï´Ù. µµ¹«Áö »ö¼Ò°¡ ÇÊ¿äÇÏ´Ù´Â »ý°¢ÀÌ µéÁö ¾Ê¾Ò½À´Ï´Ù.

´ÙÀ½¿¡ ¸»¾¸µå¸± indigo carmineÀº °ø±ÞÀÌ ºÒ¾ÈÁ¤ÇÑ »ö¼ÒÀÔ´Ï´Ù. °£È¤ indigo carmineÀÌ ¶³¾îÁú ¶§°¡ ÀÖ´Ù´Â ¸»¾¸ÀÔ´Ï´Ù. ÀÌ·² ¶§ ´ë¿ëÀ¸·Î methylene blue¸¦ ¾µ ¼ö ÀÖ½À´Ï´Ù. ÀÌ°ÍÀÌ ÇöÀç Àú¿¡°Ô´Â methylene blueÀÇ À¯ÀÏÇÑ ¿ëµµÀÔ´Ï´Ù. Áï indigo carmine ´ë¿ë Á¤µµÀÇ °¡Ä¡°¡ ÀüºÎÀÎ ¼ÀÀÔ´Ï´Ù.


@ ¸µÅ©: »ö¼Ò³»½Ã°æ chromoendoscopy

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