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[20110603. Issues on duodenal ulcer (16): surgery for duodenal ulcer]

½ÊÀÌÁöÀå±Ë¾çÀÇ ¼ö¼ú¹ýÀº ½Ã´ë¿¡ µû¶ó Å©°Ô ´Þ¶óÁ³½À´Ï´Ù. °ú°ÅÀÇ ¼ú½ÄÀ» »ìÆ캸±â À§ÇÏ¿© ´Ù½Ã 1994³âÆÇ Misievicz ÆíÀú, Diseases of the Gut and Pancreas (2nd ed) 293ÂÊÀ» ÆîĨ´Ï´Ù.

°°Àº Ã¥¿¡ ¼Ò°³µÈ ½ÊÀÌÁöÀå±Ë¾ç ¼ö¼ú ¹æ¹ýÀº (1) partial gastrectomy without vagotomy, (2) truncal vagotomay with antrectomy, (3) truncal vagotomy and drainage by gastrojejunostomy or pyloroplasty, (4) highly selective vagotomy µîÀÔ´Ï´Ù. ¿äÁòÀº Á»Ã³·³ º¸±â ¾î·Á¿î ¼ö¼úÀÔ´Ï´Ù. ¶Ç ÀÌ·± ¾ð±Þµµ ÀÖ½À´Ï´Ù. Recurrent ulceration is due in most patients to failure to achieve complete vagal denervation of the acid-pepsin-secreting area of the stomach.

±×·¯³ª H2RA°¡ ³Î¸® ¾²ÀÌ°í ÀÖ¾ú°í omeprazoleµµ ¼Ò°³µÇ¾ú´ø, ±×¸®°í HelicobacterÀÇ ¿ªÇÒ¿¡ ´ëÇÑ Ãʱ⠿¬±¸°¡ ¹ßÇ¥µÈ ½Ã´ëÀÎ 1994³â¿¡ ³ª¿Â Ã¥À̹ǷΠ°ú°ÅÀÇ ¼ö¼ú ¹æ¹ýÀ» ¼Ò°³Çϸ鼭µµ ¹ú½á Àç¹ßÀÇ ¿¹¹æº¸´Ù ¼ö¼ú ÈÄ ÇÕº´Áõ¿¡ ´ëÇÑ ¿ì·Á°¡ °­Á¶µÇ°í ÀÖ½À´Ï´Ù. ÇØ´ç ºÎºÐÀ» ¿Å±é´Ï´Ù.

The ideal operation for duodenal ulcer is one that is safe, cures the ulcer and free from undesirable effects due to altered gastrointestinal anatomy and physiology. None of the operations available is ideal, and in assessing their relative worth, safety is the overriding consideration. In the past, great emphasis was placed on avoiding recurrent ulcer, but it is now apparent that severe dumping and diarrhea may be more incapacitating and more difficult to treat.

ÃÖ±Ù¿¡´Â ½ÊÀÌÁöÀå±Ë¾çÀ¸·Î ¼ö¼úÇϴ ȯÀÚ°¡ ¸¹Áö ¾Ê½À´Ï´Ù. °£È¤ ¼ö¼ú¹Þ´Â ȯÀÚµµ minimalÇÑ ¼ú½ÄÀÌ ¾²ÀÔ´Ï´Ù. ½ÊÀÌÁöÀå±Ë¾ç õ°ø¿¡ ´ëÇÏ¿© primary repair¸¸ ÇÏ´Â ¿Ü°úÀǻ簡 ´ëºÎºÐÀÔ´Ï´Ù. Vagotomy´Â ÀØÇôÁö°í ÀÖ½À´Ï´Ù. Helicobacter¿Í PPI ´öÅÃÀÔ´Ï´Ù.

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