[20120215. Complications of EMR/ESD (41): Bleeding (5) - laboratory variation]
¾îÁ¦ ¸»¾¸µå¸° ³»¿ë¿¡ ´ëÇÑ °íÂûÀÔ´Ï´Ù. ´ÚÅÍ Tajiri°¡ "if the Hb level falls by 2 g/dL or more in comparison with the last preoperative level"À̶ó°í ¸»ÇÑ ÀÌÀ¯´Â ¹«¾ùÀϱî¿ä?
Àú´Â EMR/ESD ÈÄ Ç÷»ö¼Ò°¡ 1-2 g/dL Á¤µµ ³»·Á°¡´Â °ÍÀº ÀÖÀ» ¼ö ÀÖ´Â ÀÏÀ̶ó°í »ý°¢ÇÕ´Ï´Ù. ¿øÀÎÀº ¿©·¯°¡Áö¸¦ »ý°¢ÇÒ ¼ö ÀÖ½À´Ï´Ù.
(1) ½Ã¼ú µµÁßÀÇ ÃâÇ÷ÀÌ ¸¹¾Ò´Ù¸é ¾Æ¹«¸® ÁöÇ÷À» Àß Çß´õ¶óµµ Ç÷»ö¼Ò°¡ ¾à°£ ³»·Á°¥ ¼ö ÀÖ½À´Ï´Ù.
(2) ½Ã¼ú ÈÄ melena³ª hematemesis°¡ ¾ø´õ¶óµµ ¼Ò·®ÀÇ ÃâÇ÷·Î ÀÎÇØ Ç÷»ö¼Ò°¡ ¾à°£ ³»·Á°¥ ¼ö ÀÖ½À´Ï´Ù. ¼Ò·®ÀÇ ÃâÇ÷Àº ´ë°³ ÀúÀý·Î ¸ÜÀ¸¹Ç·Î ÀÓ»óÀû ÀÇÀÇ´Â ¾ø½À´Ï´Ù.
(3) ½Ã¼ú Àü ¾à°£ Å»¼öµÈ »óÅ¿´°í, ½Ã¼ú ÈÄ ÃæºÐÈ÷ hydration ÇÑ »óÅ¿¡¼ °Ë»ç°¡ µÇ¾ú´Ù¸é ¾Æ¹« ÀÏ ¾øÀ̵µ Ç÷»ö¼Ò°¡ ³»·Á°¥ ¼ö ÀÖ½À´Ï´Ù. ¹éÇ÷±¸¿Í Ç÷¼ÒÆǵµ ÇÔ²² ³»·Á°¡±âµµ ÇÕ´Ï´Ù. Çö´ëÀÎÀº ´©±¸³ª ¾à°£ Å»¼öµÈ »óÅ¿¡¼ »ì¾Æ°£´ÙÁö ¾Ê½À´Ï±î?
(4) °Ë»ç¿ÀÂ÷ÀÔ´Ï´Ù.
°Ë»ç¿ÀÂ÷¸¦ »ý°¢Çغ¾½Ã´Ù. ¾îÁ¦º¸´Ù Ç÷»ö¼Ò°¡ ³»·Á°¬´Ù°í º¸°í¹Þ´Â ÈÄ Çã¸ÁÇÑ °æÇèÀ» ÇϽŠÀûÀÌ ¾øÀ¸½Ê´Ï±î? Àú´Â ¸¹½À´Ï´Ù. ¾îÁ¦´Â 13.3 g/dL¿´´Âµ¥ ¿À´Ã 13.1 g/dL¶ó¸é ÁøÁ¤ ÃâÇ÷ÀÌ ÀÖ¾ú´ø °ÍÀϱî¿ä? Ȥ½Ã °°Àº sample·Î µÎ ¹ø °Ë»çÇÒ ¶§ ³ª¿Ã ¼ö ÀÖ´Â Â÷ÀÌ ¾Æ´Ò±î¿ä?
¸ðµç °Ë»ç´Â ¾à°£ÀÇ ¿ÀÂ÷¹üÀ§¸¦ °¡Áö°í ÀÖ½À´Ï´Ù. ¾ÆÁÖ ÀÛÀº º¯È´Â ¹«½ÃÇÏ´Â ÆíÀÌ ³ªÀ» ¼ö ÀÖ½À´Ï´Ù.
Henry's Clinical Diagnosis and Management by Laboratory Methods (21th ed. 2007. Saunders) 459ÂÊ "Errors in hemoglobinometry"ºÎºÐÀ» ¿ä¾àÇÏ¿© ¿Å±é´Ï´Ù.
[Errors in Hemoglobinometry]
(1) Errors inherent in the sample - Improper venipucture technique may introduce hemoconcentration, which will make hemoglobin concentration and cell counts too high.
(2) Errors inherent in the method
(3) Errors inherent in the equipment - The photometer must be calibrated in the laboratory before its initial use and must be rechecked frequently to reduce the method's error to 2% (+/- CV).
(4) Operator's errors
ÀÓÀǺñ±Þ¿©¿¡ ´ëÇÏ¿© ¼ÖÁ÷ÇØÁöÀÚ´Â Çã´ë¼® ±³¼ö´ÔÀÇ Á¦¾ð
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