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[20120611. Bezoar (2) - Pathogenesis and risk factors]
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"Ingestion of large amounts of indigestible material is not the sole requirement for bezoar formation.
The majority of patients have a predisposing factor that contributes to bezoar formation -- most commonly altered gastrointestinal anatomy from previous surgery. Bezoar formation after surgery is a result of altered gastric motility with delayed gastric emptying and a reduction of gastric accomodation, poor gastric mixing, and reduced peptic activity.
Gastroparesis is commonly observed in patients with bezoars who do not have surgically altered gastric anatomy, although not all patients with bezoars have abnormal gastric emptying scans.
Patients with comorbid illnesses such as diabetes, patients with end-stage renal disease on dialysis, or patients on mechanical ventilation have an increased risk of bezoar formation."
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