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[ADR of PPI - thrombocytopenia]
ÁßȯÀÚ½Ç Àü°øÀǵ鿡 µû¸£¸é thrombocytopeniaÀÇ ¿øÀÎÀ¸·Î PPI°¡ Áß¿äÇÏ°Ô °í·ÁµÈ´Ù°í ÇÕ´Ï´Ù.
PPI¿Í ¾î¶² Á¾·ùÀÇ ¾àÁ¦¸¦ ÇÔ²² »ç¿ëÇÏ¿´À» ¶§ ¶Ñ·ÇÇÑ thrombocytopenia°¡ ¹ß»ýÇÏ´Â °æ¿ìµµ ÀÖ´Ù°í ÇÕ´Ï´Ù. Phenytoin °ü·Ã thrombocytopenia Áõ·Ê¿¡¼ ´ÙÀ½°ú °°ÀÌ ¾ð±ÞÀÌ ÀÖ½À´Ï´Ù. "Most documented cases of thrombocytopenia occur after a week or longer of phenytoin administration with the coadministration of glucocorticoids and cimetidine or proton pump inhibitors."
PPI °ü·Ã thrombocytopeniaÀÇ ºóµµ´Â ³·Àº °Í °°½À´Ï´Ù. The prevalence of pantoprozole associated thrombocytopenia in a community hospitalÀ̶ó´Â Á¦¸ñÀÇ retrospective cohort study °á°ú´Â negative¿´½À´Ï´Ù.
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