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[Acute diverticulitis (1): anatomy of diverticulum]

¾Æ·¡ ÀÚ·á´Â EndoTODAY ±Þ¼º °Ô½Ç¿°À¸·Î ¿Å°å½À´Ï´Ù.


À§Àå°ü °Ô½ÇÀº À§Àå°üº® ÀüÃþÀÌ »ßÁ®³ª¿À´Â true diverticulum°ú Á¡¸·Ãþ¸¸ »ßÁ®³ª¿À´Â pseudodiverticulumÀ¸·Î ³ª´¹´Ï´Ù. º¸ÅëÀº pseudodiverticulumÀÔ´Ï´Ù.


Sigmoid diverticuli

PseudodiverticulumÀº vasa recti°¡ °íÀ¯±ÙÃþÀ» ¶Õ°í µé¾î°¡´Â ºÎÀ§¿¡¼­ ¹ß»ýÇÕ´Ï´Ù. Áï mesenteric taeniaÀÇ ¾çÂÊ¿¡¼­ ¹ß»ýÇÕ´Ï´Ù. ¾Æ·¡ ±×¸²¿¡¼­ ¾Ë ¼ö ÀÖµíÀÌ diverticulum Á¡¸· ¹Ù·Î ¾Æ·¡¿¡ vasa recti¶ó´Â Ç÷°üÀÌ À§Ä¡ÇϹǷΠ°£È¤ ÃâÇ÷ÀÌ ¹ß»ýÇÒ ¼ö ÀÖ´Â °ÍÀÔ´Ï´Ù.


Diverticula develop on either side of the mesenteric taenia and on the mesenteric side of the antimesenteric taenia, the taenia omentalis (TO), and taenia libera (TL). These are the sites (arrows) where the vasa recta perforate the muscularis propria and penetrate the submucosa (inset).

°á±¹ diverticulum Á¡¸· ¹Ù·Î ¾Æ·¡¿¡ vasa recti¶ó´Â Ç÷°üÀÌ À§Ä¡ÇϹǷΠ°£È¤ ÃâÇ÷ÀÌ ¹ß»ýÇÒ ¼ö ÀÖ´Â °ÍÀÔ´Ï´Ù.


2013³â 4¿ù ´ëÇѼÒÈ­±âÇÐȸ PG ÄÚ½º¿¡¼­ Diverticular disease¿¡ ´ëÇÑ ÃÖ±ÙÀÇ °³³äº¯È­¿¡ ´ëÇÑ °­ÀǸ¦ Èï¹Ì·Ó°Ô µé¾ú½À´Ï´Ù. Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights¶ó´Â ¸®ºä¿¡¼­ ºñ½ÁÇÑ ³»¿ëÀÌ ÀÖ¾î À̸¦ ¼Ò°³ÇÕ´Ï´Ù.

DiverticulumÀ» °¡Áø ȯÀÚ´Â diverticulitis attackÀÌ ¾ø¾îµµ »îÀÇ ÁúÀÌ ¶³¾îÁý´Ï´Ù. ÀÌ·± °³³äÀÌ symptomatic uncomplicated diverticular disease (SUDD)·Î ¸í¸íµÈ °Í °°½À´Ï´Ù. °Ô½Ç¿¡ ´ëÇÑ ÀüÅëÀûÀÎ ¼³¸í, Áï ¾àÇÑ ºÎºÐÀÌ »ßÁ®³ª°¡°í µ¹°°Àº °Í¿¡ ÀÇÇØ ¸·È÷¸é °Ô½Ç¿°ÀÌ µÈ´Ù´Â ÇغÎÇÐÀû ¼³¸íÀº Á¡Â÷ ¼³µæ·ÂÀ» ÀҾ°í ÀÖ½À´Ï´Ù. ´ë½Å low grade inflammation, sensory-motor nerve damage, dysbiosis µîÀ» µ¿¹ÝÇÑ irritable bowel syndrome°ú ºñ½ÁÇÑ ÁúȯÀ¸·Î ÀÌÇصǰí ÀÖ½À´Ï´Ù.

SCAD (segmental colitis associated with diverticula)¶ó´Â ¹¦ÇÑ À̸§µµ ÀÖ½À´Ï´Ù. °Ô½Ç ÁÖº¯ÀÇ ÀϺθ¸ segmentalÇÏ°Ô IBD¿Í ºñ½ÁÇÑ ¸ð½ÀÀ» º¸ÀÌ´Â »óȲÀ» ¸»ÇÕ´Ï´Ù. ¸®ºä¿¡´Â ÀÌ·± ±â¼úµµ ÀÖ½À´Ï´Ù."Case series reveal that in a small subset of patients (~10%), SCAD evolves into frank IBD, suggesting that SCAD may be a forme fruste of IBD. SCAD in perhaps the most powerful example that inflammation and diverticulosis can go hand-in-hand, and that traditional explanations for diverticular disease involving local trauma and obstruction are probably insufficient."

Diverticulosis¿¡ ´ëÇÑ ÀÌÇØ°¡ ÀÌ·¸°Ô º¯°æµÇ¸é¼­ Ä¡·á¹æÇâµµ ¿µÇâÀ» ¹Þ´Â ¸ð¾çÀÔ´Ï´Ù. Ä¡·á ºÎºÐÀº ÀÌ·± ³»¿ëÀÌ Æ÷ÇԵǾî ÀÖ½À´Ï´Ù.

1) fiber supplementation

2) mesalamine (5-ASA)

3) rifaximin

4) probiotics


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@ ÀÏ¿ø³»½Ã°æ±³½Ç ¹Ù¸¥³»½Ã°æ¿¬±¸¼Ò ÀÌÁØÇà. EndoTODAY Endoscopy Learning Center. Lee Jun Haeng