[Acute diverticulitis (1): anatomy of diverticulum]
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À§Àå°ü °Ô½ÇÀº À§Àå°üº® ÀüÃþÀÌ »ßÁ®³ª¿À´Â true diverticulum°ú Á¡¸·Ãþ¸¸ »ßÁ®³ª¿À´Â pseudodiverticulumÀ¸·Î ³ª´¹´Ï´Ù. º¸ÅëÀº pseudodiverticulumÀÔ´Ï´Ù.
Sigmoid diverticuli
PseudodiverticulumÀº vasa recti°¡ °íÀ¯±ÙÃþÀ» ¶Õ°í µé¾î°¡´Â ºÎÀ§¿¡¼ ¹ß»ýÇÕ´Ï´Ù. Áï mesenteric taeniaÀÇ ¾çÂÊ¿¡¼ ¹ß»ýÇÕ´Ï´Ù. ¾Æ·¡ ±×¸²¿¡¼ ¾Ë ¼ö ÀÖµíÀÌ diverticulum Á¡¸· ¹Ù·Î ¾Æ·¡¿¡ vasa recti¶ó´Â Ç÷°üÀÌ À§Ä¡ÇϹǷΠ°£È¤ ÃâÇ÷ÀÌ ¹ß»ýÇÒ ¼ö ÀÖ´Â °ÍÀÔ´Ï´Ù.
°á±¹ diverticulum Á¡¸· ¹Ù·Î ¾Æ·¡¿¡ vasa recti¶ó´Â Ç÷°üÀÌ À§Ä¡ÇϹǷΠ°£È¤ ÃâÇ÷ÀÌ ¹ß»ýÇÒ ¼ö ÀÖ´Â °ÍÀÔ´Ï´Ù.
2013³â 4¿ù ´ëÇѼÒȱâÇÐȸ PG ÄÚ½º¿¡¼ Diverticular disease¿¡ ´ëÇÑ ÃÖ±ÙÀÇ °³³äº¯È¿¡ ´ëÇÑ °ÀǸ¦ Èï¹Ì·Ó°Ô µé¾ú½À´Ï´Ù. Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights¶ó´Â ¸®ºä¿¡¼ ºñ½ÁÇÑ ³»¿ëÀÌ ÀÖ¾î À̸¦ ¼Ò°³ÇÕ´Ï´Ù.
DiverticulumÀ» °¡Áø ȯÀÚ´Â diverticulitis attackÀÌ ¾ø¾îµµ »îÀÇ ÁúÀÌ ¶³¾îÁý´Ï´Ù. ÀÌ·± °³³äÀÌ symptomatic uncomplicated diverticular disease (SUDD)·Î ¸í¸íµÈ °Í °°½À´Ï´Ù. °Ô½Ç¿¡ ´ëÇÑ ÀüÅëÀûÀÎ ¼³¸í, Áï ¾àÇÑ ºÎºÐÀÌ »ßÁ®³ª°¡°í µ¹°°Àº °Í¿¡ ÀÇÇØ ¸·È÷¸é °Ô½Ç¿°ÀÌ µÈ´Ù´Â ÇغÎÇÐÀû ¼³¸íÀº Á¡Â÷ ¼³µæ·ÂÀ» ÀҾ°í ÀÖ½À´Ï´Ù. ´ë½Å low grade inflammation, sensory-motor nerve damage, dysbiosis µîÀ» µ¿¹ÝÇÑ irritable bowel syndrome°ú ºñ½ÁÇÑ ÁúȯÀ¸·Î ÀÌÇصǰí ÀÖ½À´Ï´Ù.
SCAD (segmental colitis associated with diverticula)¶ó´Â ¹¦ÇÑ À̸§µµ ÀÖ½À´Ï´Ù. °Ô½Ç ÁÖº¯ÀÇ ÀϺθ¸ segmentalÇÏ°Ô IBD¿Í ºñ½ÁÇÑ ¸ð½ÀÀ» º¸ÀÌ´Â »óȲÀ» ¸»ÇÕ´Ï´Ù. ¸®ºä¿¡´Â ÀÌ·± ±â¼úµµ ÀÖ½À´Ï´Ù."Case series reveal that in a small subset of patients (~10%), SCAD evolves into frank IBD, suggesting that SCAD may be a forme fruste of IBD. SCAD in perhaps the most powerful example that inflammation and diverticulosis can go hand-in-hand, and that traditional explanations for diverticular disease involving local trauma and obstruction are probably insufficient."
Diverticulosis¿¡ ´ëÇÑ ÀÌÇØ°¡ ÀÌ·¸°Ô º¯°æµÇ¸é¼ Ä¡·á¹æÇâµµ ¿µÇâÀ» ¹Þ´Â ¸ð¾çÀÔ´Ï´Ù. Ä¡·á ºÎºÐÀº ÀÌ·± ³»¿ëÀÌ Æ÷ÇԵǾî ÀÖ½À´Ï´Ù.
1) fiber supplementation
2) mesalamine (5-ASA)
3) rifaximin
4) probiotics
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@ ÀÏ¿ø³»½Ã°æ±³½Ç ¹Ù¸¥³»½Ã°æ¿¬±¸¼Ò ÀÌÁØÇà. EndoTODAY Endoscopy Learning Center. Lee Jun Haeng