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[º¹°­°æÇ׿ª·ù¼ö¼ú. Laparoscopic anti-reflux surgery (LARS)]

1. Á¦1ȸ ´ëÇÑÀ§½Äµµ¿ª·ùÁúȯ ¼ö¼ú¿¬±¸È¸ Çмú´ëȸ

½Ã°£: 2015³â 10¿ù 31ÀÏ Åä¿äÀÏ

Àå¼Ò: °í·Á´ëÇб³ ÀÇ°ú´ëÇÐ ¹®¼÷ÀÇÇаü 1Ãþ ¿øÇü°­ÀǽÇ


1. History of Korean Antireflux Surgery Study Group (KARS) - ¾ÆÁÖ´ë ÇÑ»ó¿í

KARSÀÇ ÀüȸÀå´ÔÀ̽Š¾ÆÁÖÀÇ´ë ÇÑ»ó¿í ¼±»ý´Ô²²¼­ KARS ÀÇ ¿ª»ç¸¦ ¼Ò°³Çϼ̽À´Ï´Ù. ÃÖ±Ù ´ëÇÑÀ§¾ÏÇÐȸ »êÇÏÀÇ ¿¬±¸È¸·Î ½Â°ÝÇÏ¿© óÀ½À¸·Î Çмú´ëȸ¸¦ °³ÃÖÇÑ °Í¿¡ ´ëÇÑ ¼Òȸ¸¦ ¸»¾¸Çϼ̽À´Ï´Ù.

¹Ì±¹¿¡¼­´Â 1³â¿¡ 2¸¸ °ÇÀÇ Ç׿ª·ù¼ö¼úÀÌ ½ÃÇàµÇ´Âµ¥ ¹ÝÇÏ¿©, ¿ì¸®³ª¶ó¿¡¼­´Â 2014³â¿¡ ¾à 45°ÇÀÇ Ç׿ª·ù¼ö¼úÀÌ ½ÃÇàµÇ¾ú´Ù°í ÇÕ´Ï´Ù.

À§½Äµµ¿ª·ùÁúȯ °¡À̵å¶óÀÎ(2012) ÀÛ¼º ÀÛ¾÷¿¡ ¸î ºÐÀÇ ¿Ü°ú ¼±»ý´Ô²²¼­ Âü¼®Çϼ̴ٰí ÇÕ´Ï´Ù. 23¹ø ±Ç°í¹®ÀÌ Ç׿ª·ù ¼ö¼ú¿¡ ´ëÇÑ °ÍÀÔ´Ï´Ù.


2. How I implemented antireflux surgery - °¡Å縯´ë ±èÁøÁ¶

ȸÀåÀ̽Š±èÁøÁ¶ ¼±»ý´ÔÀÇ °­ÀÇ´Â ÀÌ·± ¸»·Î ½ÃÀÛÇÏ°í ÀÖ¾ú½À´Ï´Ù. My life is too long for just gastric cancer! I decided to be a true foregut surgeon.

ÀüÇüÀûÀÎ Áõ»ó, ƯÈ÷ regurgitationÀÌ ½ÉÇÑ È¯ÀÚ¿¡¼­ ¼ö¼úÀÇ È¿°ú´Â ÁÁ½À´Ï´Ù. ³»°ú¿¡¼­ Àü°úµÈ ȯÀÚ°¡ ¾Æ´Ñ ½º½º·Î Á¤º¸¸¦ ã¾Æº¸°í ¿Ü°úÀǻ縦 ã´Â ȯÀÚ´Â ÁÖÀÇÇØ¾ß ÇÕ´Ï´Ù. ³ª¸§ È®½ÅÀ» °¡Áö°í ÀÖÀ¸¹Ç·Î ¹®ÁøÀ» ÇÏ´õ¶óµµ ȯÀÚ ½º½º·Î ¼ö¼ú¿¡ ÀûÇÕÇÑ Á¤´äÀ» À̾߱âÇϱ⠶§¹®ÀÔ´Ï´Ù. ¹®ÁøÀÌ Á¤È®ÇÏÁö ¾Ê´Ù´Â °ÍÀÌÁö¿ä.


3. High resolution manometry - °í½ÅÀÇ´ë ¹Ú¹«ÀÎ

High resolution manometry´Â ÀüÅëÀûÀÎ manometry¿¡ ºñÇÏ¿© ¹°À» »ç¿ëÇÏÁö ¾ÊÀ¸¹Ç·Î °Ë»ç ÀÚü°¡ ½±½À´Ï´Ù. ¾Æ¿ï·¯ °á°ú Çؼ®ÀÌ ½±°í interobserver variationÀÌ Àû¾î À¯¿ëÇÕ´Ï´Ù.

¹Ú¹«ÀÎ ±³¼ö´ÔÀº ÁÖ·Î ¿ÃÇØ ³ª¿Â Chicago classification version 3.0À» Áß½ÉÀ¸·Î ¸»¾¸ÇØ Áּ̽À´Ï´Ù (Kahrilas. NM 2015).


4. Impedence test for GERD - °¡Å縯´ëÇÐ Á¶À¯°æ

Conventional pH °Ë»çÀÇ ½Ã´ë´Â °¡°í impedence pH ½Ã´ë°¡ ¿Ô½À´Ï´Ù. ¹°·Ð Bravoµµ °¡´ÉÇÏÁö¸¸ pH Á¤º¸¹Û¿¡ ¾òÀ» ¼ö ¾ø´Ù´Â ´ÜÁ¡ÀÌ ÀÖÀ¸¸ç Çö½ÇÀûÀ¸·Î´Â ¼öÀÔÀÌ Áß´ÜµÇ¾î ½ÃÇàÀÌ ¾î·Æ½À´Ï´Ù. Impedence °Ë»ç °á°ú´Â Áõ»ó°ú ¿¬°üÁö¾î Çؼ®ÇØ¾ß ÇÕ´Ï´Ù. ºñ·Ï Á¤»óÀ̶ó´Â °á°ú¶ó°í º¸°íµÇ´õ¶óµµ Áõ»ó°ú Àß matching Çϸé Áø´ÜÀÇ ´Ü¼­¸¦ ã±âµµ ÇÕ´Ï´Ù.


5. ÃÊû¿¬ÀÚ °­ÀÇ - Guilherme M Campos (Virginia Commonwealth University)

¹Ì±¹»ç¶÷µéÀÌ heartburnÀ̶ó°í Çصµ ±× Àǹ̰¡ ´Ù¸£¹Ç·Î ȯÀÚÀÇ ÁøÂ¥ Áõ»óÀÌ ¹«¾ùÀÎÁö Àß µûÁ®ºÁ¾ß ÇÕ´Ï´Ù.

Three essentials of laparoscopic antireflyx surgery
1) Reduction of hiatal hernia with hernia sac - Excision / Division
2) Closure of diaphragmatic hiatus
3) Fundiplication

New technologies - Campos ¹Ú»ç´Â ¾à¹°Ä¡·á¿Í Ç׿ª·ù¼ö¼úÀÇ Áß°£´Ü°è Ä¡·á·Î °£ÁÖÇÏ°í ÀÖ¾ú½À´Ï´Ù.


1) Stretta (low frequency RFA)
2) Transoral incisionless fundoplication (TIF)
3) LINX
4) EndoStim therapy (LES electrical stimulation)
5) MUSE system

Rise and fall of anti-reflux surgery in US

Spechler ³í¹®ÀÌ µÎ¹ø ³ª¿Â´Ù´Â Á¡ÀÌ Èï¹Ì·Î¿ü½À´Ï´Ù. °æÇèÀÌ ¾ø´Â SurgeonÀÌ ¸¹´Ù.


6. POEM - ¿¬¼¼´ëÇб³ Á¤Çö¼ö

Anterior vs Posterior myotomy
- Anterior myotomy: continuing toward the lesser curve of the stomach potentially avoides damage to the sling collar muscle, which is major component of the angle of His → to minimize post-procedure reflux (Angle of His°¡ À¯ÁöµÈ´Ù´Â ÀǹÌ)
- Posterior myotomy: better relief of dysphagia because of sling fibers but at the expense of mild reflux (Angle of His°¡ ¸Á°¡Áø´Ù´Â ÀǹÌ)

2015³â 8¿ù±îÁö ¿¬¼¼´ëÇб³(½ÅÃÌ+°­³²)¿¡¼­´Â POEM 22¿¹¸¦ ½ÃÇàÇÏ¿´´Ù°í ÇÕ´Ï´Ù. ¼ºÀûÀº ¸Å¿ì ÁÁ¾Ò½À´Ï´Ù.

Patel µîÀÌ ºÐ¼®ÇÑ °¡Àå ÃÖ±Ù±îÁöÀÇ ÀÚ·áÀÔ´Ï´Ù (Patel K. Dis Esophagus 2015). ´Ù ÁÁÀºµ¥ ÇÑ ¸íÀÌ Á×¾ú±º¿ä.

Minor operative adverse events included capno/pneumo-peritoneum (30.6%), capno/pneumo-thorax (11.0%) and subcutaneous emphysema (31.6%). Major operative adverse events included mediastinal leak (0.3%), postoperative bleeding (1.1%) and a single mortality (0.09%). There was an improvement in lower esophageal sphincter pressure and timed barium esophagram column height of 66% and 80% post-POEM, respectively. Symptom improvement was demonstrated with a pre- and post-POEM Eckardt score ¡¾ standard deviation of 6.8 ¡¾ 1.0 and 1.2 ¡¾ 0.6, respectively. Pre- and post-POEM endoscopy showed esophagitis in 0% and 19% of patients, respectively.

@ Âü°íÀÚ·á: EndoTODAY ½ÄµµÀ̿ϺҴÉÁõ°ú POEM


[References]

1) EndoTODAY Ç׿ª·ù¼ö¼ú

© ÀÏ¿ø³»½Ã°æ±³½Ç ¹Ù¸¥³»½Ã°æ¿¬±¸¼Ò ÀÌÁØÇà. EndoTODAY Endoscopy Learning Center. Lee Jun Haeng.