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[ÀÎõ½Ã°³¿ø³»°úÀÇ»çȸ]


1. ³ëÀÎ ³»°úÇÐ (°¡Å縯ÀÇ´ë Àü´ë¼ö)

Àü´ë¼ö ±³¼ö´ÔÀº ³ëÀÎÀÌ ¾àÇØÁö´Â ¿øÀÎÀÇ Çϳª·Î ¿µ¾ç ºÎÁ·, ƯÈ÷ ´Ü¹éÁú ºÎÁ·À» °­Á¶ÇÏ¿´½À´Ï´Ù. ÇѸ¶µð·Î °í±â¸¦ ÀÚÁÖ ¸¹ÀÌ ¸ÔÀ¸¶ó´Â À̾߱⿴½À´Ï´Ù.

¾à¹°À» ÁÖÀÇÇØ¾ß ÇÕ´Ï´Ù.

NSAIDs´Â analgesic dose¿Í anti-inflammatory dose°¡ ´Ù¸¨´Ï´Ù.

Analgesics (OA)Anti-inflammatory (RA)
Meloxicam7.5 mg qd7.5 mg bid or 15 mg qd
Naproxen500 mg qd500 mg bid
Ibuprofen400 mg tid800 mg tid
Celecoxib100 mg bid or 200 mg qd200 mg bid

Acetaminophen

Vitamin D: ÇÞºµ¿¡ ÀÇÇØ »ý¼ºµÇ´Â endogenous vitamin D´Â °Ç°­¿¡ µµ¿òÀÌ µÇÁö¸¸ ¸Ô´Â exogenous vitamin D´Â ´ë»çÀÛ¿ëÀÌ ´Þ¶ó¼­ µµ¿òÀÌ µÇÁö ¾Ê½À´Ï´Ù. Exogenous vitamin D´Â 1,25(OH)2D°¡ artery wall°ú plaque¿¡ ÃàÀûµÇ¾î ¿ÀÈ÷·Á °Ç°­¿¡ ÇØ°¡ µÉ ¼öµµ ÀÖ½À´Ï´Ù. Vitamin D°¡ ¸¹À¸¸é cardiovascular event°¡ Áõ°¡ÇÑ´Ù´Â ÀÚ·áµµ ÀÖ½À´Ï´Ù (Circ Res 2018;122:1576). Vitamin D¸¦ ¸Ô´Â´Ù°í °ñÀýÀÌ °¨¼ÒµÇÁö ¾Ê½À´Ï´Ù (JAMA 2017;318:2466). °á±¹ vitamin D¸¦ ¸Ôµµ·Ï ±ÇÇؾßÇϴ ȯÀÚ´Â ¾ø´Ù´Â °ÍÀÔ´Ï´Ù.

Vitamin D supplement
(USPSTF recommendation, JAMA 2018;319:1599)
Prevention of falls at high rish >= 65 yearsNot recommended
Primary prevention of fracture >= 50 years
(Men and premenopausal women)
Insufficient evidence
Primary prevention of fracture >= 50 years
(Postmenopausal women)
<= 400 IU, not recommended
> 400 IU, insufficient evidence


2. ¾ß¿Ü È°µ¿¿¡¼­ ¸¸³¯ ¼ö ÀÖ´Â °¨¿°¼º ¿­¼ºÁúȯ (°¡Ãµ´ëÇб³ ±æº´¿ø °¨¿°³»°ú ¾öÁß½Ä)

2018³âÀº ¿©·¯ ¿­¼ºÁúȯÀÌ ÁÙ¾ú½À´Ï´Ù. ¿ÃÇØ ¿©¸§ÀÌ ±Ø½ÉÇÏ°Ô ´õ¿ü±â ¶§¹®¿¡ ¸ð±â³ª Áøµå±â µîÀÇ »ýÈ°»ç°¡ ÆíÇÏ¿´±â ¶§¹®ÀÌ ¾Æ´Ñ°¡ ÃßÁ¤µË´Ï´Ù.


1) SFTS (ÁßÁõ¿­¼ºÇ÷¼ÒÆÇ°¨¼ÒÁõ)

ö»õ¿¡ ÀÇÇØ ÂüÁøµå±â°¡ ¿ì¸®³ª¶ó·Î ¿Å°Ü¿Â °ÍÀ¸·Î ÃßÁ¤µÇ°í ÀÖ½À´Ï´Ù.

ÂüÁøµå±â¿¡ ÀÇÇØ ¹°¸° ÀÚ±¹¿¡ Áøµå±â°¡ ¹ÚÇô ÀÖ´Â °æ¿ì°¡ ÀÖ½À´Ï´Ù. ¼ÕÀ¸·Î Á¦°ÅÇÏ´Â µµÁß Áøµå±â°¡ ºñƲ¾îÁö°Å³ª, ȸÀüÇÏ¿© ºÎ¼ÅÁö°Å³ª, ¿ÏÀüÈ÷ ºüÁöÁö ¾ÊÀ¸¸é viral load°¡ Áõ°¡ÇϹǷΠÀ§ÇèÇÕ´Ï´Ù. ÇɼÂÀ¸·Î 90µµ·Î µé¾î¿Ã¸®´Â ¹æ¹ýÀ¸·Î Á¦°ÅÇØ¾ß ÇÕ´Ï´Ù.


2) ÂêÂê°¡¹«½Ãº´

Ãæûµµ À̳² Áö¿ªÀº º¸·É Ç÷ûÇüÀÌ ¸¹°í less toxic ÇÕ´Ï´Ù. °­¿øµµ¿¡¼­´Â Gilliam Ç÷ûÇüÀÌ ¸¹Àºµ¥ more toxic ÇÕ´Ï´Ù.

¹ã³ª¹«¿¡ ÅÐÁøµå±â°¡ ¸¹½À´Ï´Ù. ¹ãÀ» µþ ¶§ °¨¿°µÇ±âµµ ÇÕ´Ï´Ù.

±Ø½ÉÇÑ µÎÅë°ú ±ÙÀ°Åë, Eschar, ¹ßÁø, ±¹¼Ò.

3ÀÏ ÀÌ»ó ¿­ÀÌ ³ª°í, 3¹ø ÀÌ»ó ¿­ÀÌ ³ª°í, ±âħ/°¡·¡/Ä๰ÀÌ ¾øÀ¸¸é °¨±â¸ö»ìÀÌ ¾Æ´Ï¶ó ´Ù¸¥ ÁúȯÀ» ÀǽÉÇØ¾ß ÇÕ´Ï´Ù.

¾ÆÁÖ Ãʱ⿡´Â serology°¡ À½¼ºÀ¸·Î ³ª¿Ã ¼ö ÀÖÀ¸¹Ç·Î eschar¸¸À¸·Î Áø´ÜÇÒ ¼ö ÀÖ½À´Ï´Ù.


[FAQ]

[2018-11-24. ÀÌÁØÇà Áú¹®]

ÇÑ Áý´ãȸ¿¡¼­ °æ³²Áö¿ª ȯÀÚÀε¥ eschar¶ó°í »ý°¢ÇÏ¿´´ø º´¼Ò°¡ ÀÖ¾ú´Âµ¥ Ç÷¾×°Ë»ç¿¡¼­ SFTS·Î Áø´ÜµÈ ȯÀÚ¸¦ º» ÀûÀÌ ÀÖ½À´Ï´Ù. ÂüÁøµå±â¿¡ ÀÇÇÑ ¹°¸° ÀÚ±¹°ú scrub typhusÀÇ eschar¸¦ ±¸º°ÇÒ ¼ö ÀÖ´Â ¹æ¹ýÀº? ÂüÁøµå±â(tick)¿¡ ÀÇÇÑ SFTS¿Í ÅÐÁøµå±â(mite)¿¡ ÀÇÇÑ scrub typhusÀÇ º¹ÇÕ°¨¿°¿¹´Â ¾ø´ÂÁö¿ä? Ç÷û°Ë»çÀÇ cross-reactivity´Â ¾øÀ»±î¿ä?

[2018-11-24. ¾öÁᫎ ±³¼ö´Ô ´äº¯]

Eschar·Î º¸À̴µ¥¿ä, scrub typhus°¡ °è¼Ó À½¼ºÀ̾ú´Ù¸é murine typhus µî¿¡ ´ëÇÑ Ç÷û°Ë»çµµ ÇØ º¸´Â °ÍÀÌ ÁÁ°Ú½À´Ï´Ù. µ¿½Ã°¨¿°Àº ÀÌ·Ð»ó °¡´ÉÇÏ°ÚÁö¸¸ ¸Å¿ì µå¹® »óȲÀÏ °Í °°½À´Ï´Ù. Á¤È®ÇÑ ÀÚ·á´Â ¾Ë ¼ö ¾øÀ¸³ª SFTS´Â ¹ÙÀÌ·¯½º ÁúȯÀÌ°í, scrub typhus´Â ¸®ÄÏÂ÷ ÁúȯÀ̹ǷΠ°Ë»çÀÇ cross-reactvity´Â ³·À» °Í °°½À´Ï´Ù. SFTS´Â RT-PCR·Î Áø´ÜÇÕ´Ï´Ù.



© ÀÏ¿ø³»½Ã°æ±³½Ç ¹Ù¸¥³»½Ã°æ¿¬±¸¼Ò ÀÌÁØÇà. EndoTODAY Endoscopy Learning Center. Lee Jun Haeng.