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[¾Öµ¶ÀÚ Áõ·Ê ÆíÁö 41 - ´Ù¾çÇÑ Áõ·Ê]

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[2019-12-23. ¾Öµ¶ÀÚ ÆíÁö]

±³¼ö´Ô ¾È³çÇϼ¼¿ä! ¼Û³âȸ ¶§ ºÆ¾î¼­ ¹Ý°©°í Áñ°Å¿ü½À´Ï´Ù. EndoTODAY´Â ¿©ÀüÈ÷ Àß ¹Þ¾Æº¸°í ÀÖÀ¸¸ç, ¿©ÀüÈ÷ ±ÞÇÒ ¶§ ·¹ÆÛ·±½º·Î¼­ ´Ã µµ¿òÀ» ¹Þ°í ÀÖ½À´Ï´Ù.

¿ÃÇØ°¡ ¹ú½á Áö³ª°¡°í ÀÖ½À´Ï´Ù... ·ÎÄÿ¡¼­ 10°³¿ù °¡±îÀÌ ÀûÀÀÇÏ°í ¶Ç ¸¹Àº ¼öÀÇ ³»½Ã°æ°ú Áø·á¸¦ ÇÏ´Ù º¸´Ï ·ÎÄà ³ª¸§ÀÇ Àç¹Õ´Â ÄÉÀ̽º°¡ À־ ¿ì¸® ÈĹèµé°ú, ±³¼ö´Ô°ú °øÀ¯Çغ¸°íÀÚ ÀڷḦ º¸³»µå¸³´Ï´Ù.

»ç½Ç ÀúÈñ º´¿ø¿¡¼­µµ ÇÑ ´Þ¿¡ ÇÑ ¹ø ³»½Ã°æ Áý´ãȸ¸¦ ÇÏ´ÂÁö¶ó, ±×°Å ÁغñÇϸ鼭 È¥ÀÚ º¸±â¿¡ ¾Æ±õ´Ù ½Í¾î¼­ °øÀ¯Çغ¾´Ï´Ù ^^ »ï¼ºÀ¸·Î Àü¿ø½ÃŲ ȯÀڵ鵵 ´Ù¼ö ÀÖ¾î, ³ª¿Í¼­µµ ±³¼ö´ÔµéÀ» ¹Ï°í ÀÇÁöÇÏ°Ô µÇ´Â±¸³ª ½Í½À´Ï´Ù.


1. ÀþÀº ¿©¼º¿¡¼­ÀÇ Ç÷¼º ¼³»ç¿Í º¹Åë - Klebsiella oxytoca colitis (r/o antibiotics-associated)

[ÀÌÁØÇà comment] Tissue culture¸¦ ÅëÇÏ¿© ¿øÀαձîÁö ¹àÇû´Ù´Ï Á¤¸» ÈǸ¢ÇÑ ÀÏÀ» Çϼ̽À´Ï´Ù. ºñ½ÁÇÑ Áõ·Ê°¡ º¸°íµÈ °ÍÀÌ À־ ¾Æ·¡¿¡ ¿Å±é´Ï´Ù.

Antibiotic-associated hemorrhagic colitis caused by cytotoxin-producing Klebsiella oxytoca

Klebsiella oxytoca was recently described as the causative organism for antibiotic-associated hemorrhagic colitis (AAHC). It is currently not known if this novel gastrointestinal infection exists in children. AAHC is usually preceded by antibiotic treatment with penicillins, which are frequently prescribed for pediatric patients. In contrast to colitis caused by Clostridium difficile, colitis caused by K oxytoca is usually segmental and located predominantly in the right colon. Patients with AAHC typically present with abdominal pain and almost always bloody diarrhea. We present here the case of an adolescent patient who developed acute abdominal pain and bloody diarrhea after antibiotic treatment for acute urinary infection with amoxicillin-clavulanate. Right-sided colitis was verified by abdominal sonography. Stool culture tested negative for common gastrointestinal pathogens but yielded K oxytoca. Toxin production of the isolated strain was verified in a cell-culture assay. Cessation of the causative antibiotic treatment led to rapid improvement and cessation of bloody diarrhea within 3 days. We report here the first (to our knowledge) pediatric case of K oxytoca infection causing AAHC. Establishing the diagnosis of AAHC by culturing K oxytoca and demonstrating right-sided colitis with noninvasive imaging studies might prevent unnecessary invasive procedures in children with bloody diarrhea.


2. Amebic colitis ¸î Áõ·Ê

3´Þ ÀüºÎÅÍ ½ÃÀÛµÈ ¹èº¯½Ã ÃâÇ÷, ÀæÀº ¹èº¯°ú ¼³°ú, º¹Åë. ¿ÜºÎº´¿ø¿¡¼­ ±Ë¾ç¼º ´ëÀå¿° ÀǽÉÇÏ¿© Ä¡·á

ÃÖ±Ù ÇÏ·ç 5ȸÀÇ Ç÷¼º Á¡¾×º¯. ÇØ¿Ü ¿©Çà ¿©·¯ Â÷·Ê, ÃÖ±Ù Áß±¹ ¿©Çà

¹«Áõ»ó °ÇÁø ³»½Ã°æ. ¿©Çà·Â ¾øÀ½. ÅÔ¹ç °¡Áö°í °è½Å ºÐ. º¹ºÎ ÃÊÀ½ÆÄ´Â Á¤»ó

7°³¿ù ÀüºÎÅÍ Ç÷º¯, Á¡¾×º¯, tenesmus. ¿ÜºÎº´¿ø¼­ nonspecific proctitis, ulcerative proctitis ÀǽÉÇÏ¿¡ Ä¡·á¹ÞÀº ¹Ù ÀÖÀ½.

* Âü°í: EndoTODAY ÀÌÁú¾Æ¸Þ¹Ù


3. CMV colitis

Àü¸³¼±¾Ï ȯÀÚ·Î FU CT ¿¡¼­ ´ëÀå¾Ï Àǽɵȴ٠ÇÏ¿© ½ÃÇàÇÑ colonoscopy °á°úÀÓ. Áõ»ó ¾ø¾úÀ½.


4. AGC versus BGU

¾î´À ÂÊÀÌ À§¾ÏÀϱî¿ä?

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[ÀÌÁØÇà comment] ÁÂÃø Áõ·Ê°¡ ¾ÏÀ̶ó´Â °ÍÀº ±Ý¹æ ¾Ë ¼ö ÀÖ½À´Ï´Ù. ÀüÇüÀûÀÎ º¸¸¸ 2ÇüÀ¸·Î¼­ ±Ë¾çºÎ ÁÖº¯ÀÇ ºñ±³Àû ±ÕÀÏÇÑ 1cm Á¤µµÀÇ heaped up bank °°Àº ¸ð¾çÀÌ¸é ´Ù¼Ò ºÒ±ÔÄ¢ÇÑ Ç¥¸é ±¸Á¶¸¦ º¸ÀÌ°í ÀÖ½À´Ï´Ù. ±Ë¾çºÎ edge´Â ÀϺδ sharpÇÏÁö¸¸ 6½ÃºÎÅÍ 9½Ã±îÁö¿Í 12½Ã ¹æÇâÀº blurredµÇ¸é¼­ ÀϺκп¡¼­ »ï°¢Çü ¸ð¾çÀÇ overridingµµ º¸ÀÔ´Ï´Ù. ¹®Á¦´Â ¿ìÃøÀä... ±Ë¾çºÎ´Â ÀÛÁö¸¸ ±íÀ¸¸ç edge´Â blurred µÇ¾î ÀÖ½À´Ï´Ù. ÇÔ¸ôºÎ ÁÖº¯ÀÇ heaped up bank ºÎºÐÀº µÎ²²°¡ ±ÕÀÏÇÏÁö ¾Ê°í ¹«¾ùº¸´Ùµµ 1½Ã ¹æÇâ¿¡¼­ ¸î °³ÀÇ fold°¡ ²ø·Á¿À¸é¼­ ±Ë¾çºÎ·Î converging ÇÏ´Â ¸ð½ÀÀÔ´Ï´Ù. °Ô´Ù°¡ 1½Ã ¹æÇâ¿¡¼­ ²ø·Á¿À´Â foldÀÇ Ç¥¸é¿¡´Â erosionµµ ÀÖ½À´Ï´Ù. ÀÌ·¯ÇÑ ¼Ò°ßÀº recurrent ulcerÀÇ scar Á߾Ӻο¡¼­ ±Ë¾çÀÌ Àç¹ßÇÑ °ÍÀ¸·Î Çؼ®µÇ´Â ¼Ò°ßÀÔ´Ï´Ù. Á¶Á÷°Ë»çµµ ÀÌ¿¡ ÇÕ´çÇÏ°Ô ³ª¿Ô´Ù´Ï Áø´Ü¿¡´Â ¹«¸®°¡ ¾øÀ» °Í °°½À´Ï´Ù.


5. À§¾Ï

F/90. ¼ö ÁÖ ÀÌ»ó Áö¼ÓµÈ ¸íÄ¡ ÅëÁõ ¼ÒÈ­ºÒ·® µîÀ» ÁÖ¼Ò·Î ³»¿ø. óÀ½ºÎÅÍ ³»½Ã°æ °Ë»ç¸¦ ÇÏÁö´Â ¾Ê¾Ò°í ¾à°£ÀÇ Åõ¾à¿¡µµ ºÒ±¸ÇÏ°í È£ÀüµÇÁö ¾Ê¾Æ ÃÊÀ½Æĸ¦ ½ÃÇàÇÑ °á°ú À§³»¿¡ À½½Ä¹°ÀÌ ¸¹ÀÌ ³²¾ÆÀÖ´Â °ÍÀ¸·Î ¹Ì·ç¾î antral lesionÀÌ ÀÇ½ÉµÈ´Ù°í º¸°íµÊ. ³»½Ã°æ¿¡¼­´Â ÀüÁ¤ºÎÀÇ ulceroinfiltrative cancer¿´À¸¸ç ½ÊÀÌÁöÀåÀ¸·Î´Â ÁøÀÔÇÒ ¼ö ÀÖ¾úÀ½. º´¸®°á°ú: TUBULAR ADENOCARCINOMA, moderately differentiated

F/62. À§Ã¼ºÎ Èĺ® º´¼Ò·Î ÇϹÙÅ͸é missÇÒ »· ÇÏ¿´½À´Ï´Ù.

F/80. ¹«Áõ»ó °ÇÁø. ÀüÁ¤ºÎ ¼Ò¸¸À» °ÅÀÇ ´Ù Â÷ÁöÇÏ´Â ±íÀº ±Ë¾çÀ» µ¿¹ÝÇÑ Á¾¾çÀ̾ú´Âµ¥µµ ȯÀÚ´Â ÀüÇô Áõ»óÀÌ ¾ø¾ú½À´Ï´Ù.

M/84. Adenocarcinoma, moderately differentiated. ¸¶Áö¸· ³»½Ã°æ 4³â Àü

M/70. Adenocarcinoma, poorly differentiated with signet ring cell carcinomas

M/74. Poorly cohesive carcinoma

F/56. Signet ring cell carcinoma

M/57. Signet ring cell carcinoma

F/61. Poorly cohesive carcinoma, signet ring cell type


6. ½Äµµ¾Ï

M/72. 35-37cm from UI, squamous cell carcinoma, moderately differentiated → Ivor-Lewis ¼ö¼úÀ» ¹ÞÀ¸¼Ì°í ÃÖÁ¾ º´±â´Â T1bN0M0

M/72. 30cm from UI, squamous cell carcinoma, moderately differentiated


[References]

1) EndoTODAY ¾Öµ¶ÀÚ Áõ·Ê ÆíÁö

© ÀÏ¿ø³»½Ã°æ±³½Ç ¹Ù¸¥³»½Ã°æ¿¬±¸¼Ò ÀÌÁØÇà. EndoTODAY Endoscopy Learning Center. Lee Jun Haeng.