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[ÀÏ¿ø³»½Ã°æ±³½Ç ¸ñ¿äÁ¡½ÉÁý´ãȸ 2016-3-31]

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1. Pathology of the ischemic colitis

¸ñ¿äÁý´ãȸ¿¡¼­ ischemic colitis Áõ·Ê°¡ ÀÖ¾ú½À´Ï´Ù. ÀÌ¿¡ ´ëÇÑ º´¸® ¼Ò°ßÀ» ±è¼ø¿µ ¼±»ý´Ô²²¼­ Á¤¸®Çϼ̽À´Ï´Ù.

Ischemic colitis (H&E). Necrosis of superficial crypts with viable crypt bases is present (arrows). The changes are pauciinflammatory and characteristic hyalinization of the lamina propria with congestion and red cell extravasation (arrowheads) is seen. There is edema of the submucosa


Áõ·Ê 2. Herpetic esophagitis (s/p total gastrectomy due to gastric cancer)

Sleisenger Ã¥¿¡¼­ ¿Å±é´Ï´Ù. "The endoscopic appearance is characterized by diffuse friability; ulceration; and exudates, mostly in the distal esophagus. Classically, the earliest esophageal lesions are rounded 1- to 3-mm vesicles in the mid to distal esophagus, the centers of which slough to form discrete circumscribed ulcers with raised edges. These lesions can also be appreciated radiographically."

* ÂüÁ¶: EndoTODAY ¹ÙÀÌ·¯½º ½Äµµ¿°


Áõ·Ê 3. Atypical regenerating glands

ù Á¶Á÷°Ë»ç°¡ H. pylori (+) gastritis, active with ulcer and atypical regenerating glands·Î ³ª¿ÔÁö¸¸ Á¦±ÕÄ¡·á¿Í ±Ë¾çÄ¡·á ÈÄ È£ÀüµÇ¾ú°í Àå±â °æ°ú°üÂû¿¡¼­µµ ¹®Á¦°¡ ¾ø¾ú½À´Ï´Ù. Atypical regenerating glands´Â °£È¤ ¾ÏÀÏ ¼öµµ ÀÖÁö¸¸ ´Ù¼ö´Â ÀÌ¿Í °°ÀÌ ¾ç¼º ÁúȯÀ¸·Î ³ª¿É´Ï´Ù. ¿©ÇÏÆ° ÁÖÀÇÇØ¾ß ÇÕ´Ï´Ù.


Áõ·Ê 4. Duodenal adenocarcinoma

¿ÜºÎ ³»½Ã°æ¿¡¼­ "duodenal 3rd part ulcer and stricture (biopsy: atypical glands)" ¼Ò°ßÀ¸·Î ÀÇ·ÚµÈ ºÐÀ¸·Î ³»½Ã°æ Àç°Ë¿¡¼­ M/D adenocarcinoma·Î ¼ö¼úÇÑ Áõ·ÊÀÔ´Ï´Ù. ³»½Ã°æ ¼Ò°ß°ú ¼ö¼ú º´¸®¸¦ ¼Ò°³ÇÕ´Ï´Ù.

³»½Ã°æ ¼Ò°ß: Duodenal 2nd to 3rd portionºÎÀ§¿¡ lumenÀ» encirclingÇÏ´Â mass °üÂûµÇ¾úÀ¸¸ç ¼Ò¾Æ¿ë ´ëÀå ³»½Ã°æÀ» ÀÌ¿ëÇÏ¿© ÁøÀÔ ½ÃµµÇÏ¿´À¸³ª massÀÇ À§Ä¡°¡ angulation Á÷ÈÄÀÌ°í lumenÀÌ Á¼¾ÆÁ®ÀÖ¾î scopeÀÌ Åë°úµÇÁö ¸øÇß½À´Ï´Ù. À§³»½Ã°æÀ¸·Î ¹Ù²Ù¾î tryÇßÀ¸³ª ÃÖ´ëÇÑ »ðÀÔÇصµ massÀÇ ÀÔ±¸±îÁö ¹Û¿¡ µµ´ÞÇÏÁö ¸øÇÏ¿©, ´Ù½Ã ¼Ò¾Æ¿ë ´ëÀå³»½Ã°æ¿¡ capÀ» ÀåÂøÈÄ tryÇßÀ¸³ª ¿ª½Ã ÁøÀÔºÒ°¡´ÉÇÏ¿© ÃÖ´ëÇÑ forcepÀ» ¹Ð¾î³Ö¾î Á¶Á÷°Ë»ç¸¦ ½ÃÇàÇß½À´Ï´Ù.

DUODENAL CANCER
1. Type of specimen : PPPD
2. Histopathologic Diagnosis : Adenocarcinoma, moderately differentiated
(1) Tumor site : duodenal
(2) Tumor size : 4.5x4 cm
(3) T3 : Tumor invades through the muscularis propria into the subserosa
(4) Involvement of pancreas: absent
(5) N1 : Regional lymph node metastasis (2/16: "peri-SMA tissue" for frozen section-1, 0/1; "LN8,12", 0/6; "periCBD&peripancreatic LN", 1/3; periduodenal, 1/2; peripancreatic, 0/4)
(6) M0 : No distant metastasis
(7) Negative (pancreas, common bile duct, retropancreatic) resection margins


»óºÎÀ§Àå°ü ³»½Ã°æÀ¸·Î µµ´ÞÇÒ ¼ö ÀÖ´Â ºÎÀ§¿¡ À§Ä¡ÇÑ ½ÊÀÌÁöÀå¾Ï ¸î Áõ·Ê¸¦ ¼Ò°³ÇÕ´Ï´Ù.

ÃÊ°í·ÉÀ¸·Î ¼ö¼úÀ» ¸øÇϽðí 1³â Á¶±Ý ³Ñ¾î obstruction Áõ»ó ¹ß»ý

Partial resectionÀ¸·Î Ä¡·áÇÏ¿´°í Á¡¸·¿¡ ±¹ÇÑµÈ 0.6cm ¾ÏÀ̾ú½À´Ï´Ù. ÃÖ±Ù °°¾Æ¼­´Â ³»½Ã°æ ÀýÁ¦¼ú·Î Ä¡·áÇÒ ¼ö ÀÖ´Ù°í »ý°¢µË´Ï´Ù.

M/D adenocarcinoma, 3.5 x 3 cm, extension to subserosa, metastasis to 3 out of 10 regional lymph nodes

Duodenal cancer (M/D adenocarcinoma, 4 x 2 cm, extension to periduodenal soft tissue and pancreas, LN 1/34) + stomach cancer

Obstruction (+), hepatic metastasis (+)

Poorly differentiated carcinoma

Mucinous adenocarcinoma, 5 x 5 x 3 cm, directly invades other organs (pancreas), involvement of vessel (SMA and SMV: op. record without histologic evaluation), regional lymph node metastasis (13/16)

O & C due to SMA, pancrease, stomach metastasis

Bowel habit change·Î ´ëÀå³»½Ã°æ¿¡¼­ ¿ìÃø ´ëÀå¾ÏÀÌ ¹ß°ßµÇ¾ú°í ¿ì¿¬È÷ ½ÃÇàÇÑ À§³»½Ã°æ¿¡¼­ duodenal adenocarcinomaµµ ÇÔ²² Áø´ÜµÇ¾úÀ½. Whipple ¼ö¼ú°ú right hemicolectomy¸¦ µ¿½Ã¿¡ ½ÃÇàÇÏ¿´À½.

Duodenal papillary adenocarcinoma

Duodenal signet ring cell carcinoma

Depressed type FAP-associated early duodenal carcinoma



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