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[Thursday Endoscopy Conference 20171130]

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1. Colon cancer SM invasion

³»½Ã°æ °Ë»ç¸¦ ÇϽŠÀӻ󰭻粲¼­ "AV 38cmÀÇ º´º¯¿¡ ´ëÇؼ­´Â »ý°¢º¸´Ù ±íÀ» ¼ö ÀÖ¾î º¸ÀÌ°í cancer °¡´É¼ºµµ ÀϺΠÀÖ¾î º¸¿© °¡º±°Ô biopsy 1Â÷·Ê¸¸ ½ÃÇàÇÏ¿´½À´Ï´Ù. °á°ú È®ÀÎ ÈÄ ESD µî °¡´É¼º¿¡ ´ëÇØ ³íÀÇ ÇÊ¿äÇÒ °ÍÀ¸·Î »ý°¢µË´Ï´Ù."¶ó°í °á°ú¸¦ ³²±â¼Ì´ø ȯÀÚÀÔ´Ï´Ù. ¹«Ã´ ÀûÀýÇÑ ÀÏ·Î »ý°¢Çß½À´Ï´Ù. ³»½Ã°æ °á°úÁö¿¡ ÀÚ½ÅÀÇ ÀÇ°ßÀ» Àû±ØÀûÀ¸·Î ³²±â´Â °ÍÀº ÁÁÀº ÀÏÀÔ´Ï´Ù.

Á¶Á÷°Ë»ç¿¡¼­´Â ¾ÏÀÌ ³ª¿Ô°í ESD°¡ ½ÃÇàµÇ¾ú´Âµ¥ ¾Æ·¡ÀÇ °á°úÀÎÁö¶ó ¾Æ½±°Ôµµ ¼ö¼úÀÌ ÇÊ¿äÇÏ¿´½À´Ï´Ù.


Colon, distal D-colon, ESD :
. Adenocarcinoma, well differentiated
1. Location : descending colon
2. Gross type : polypoid
3. Size : 1x0.5 cm
4. Depth of invasion : invades submucosa (pT1), [depth of SM invasion : 1300§­]
5. Resection margin: free from carcinoma, safety margin: proximal 0.2 cm, distal 0.2 cm, anterior 0.2 cm, posterior 0.2 cm, deep 100 §­
6. Lymphatic invasion : not identified
7. Venous invasion : not identified
8. Perineural invasion : not identified
9. Tumor budding : negative
10. Micropapillary component : No


2. Superficial spreading type EGC

2015³â ȯÀÚÀÔ´Ï´Ù. 40´ë Áß¹Ý ³²¼ºÀÔ´Ï´Ù. °úÀ½ ÈÄ ¹ß»ýÇÑ º¹ÅëÀ¸·Î ³»½Ã°æ °Ë»ç¸¦ ¹ÞÀ¸½Å ÈÄ ÀǷڵǾú½À´Ï´Ù. ¾î¶»°Ô »ý°¢ÇϽʴϱî?

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À§°¢ Èĺ®ÀÇ ¶Ñ·ÇÇÑ ¾Ïº´¼Ò°¡ ÀÖ¾ú°í À§Ã¼ºÎ ¼Ò¸¸¿¡µµ µÎ °³ÀÇ ÀÛÀº ±Ë¾çÀÌ ÀÖ¾ú½À´Ï´Ù. »çÀÌÀÇ Á¡¸·µµ ¸ðµÎ Âî±ÛÂî±Û Çß½À´Ï´Ù. ÇÔ¸ôºÎ ¼¼°÷¿¡¼­ Á¶Á÷°Ë»ç¸¦ Çߴµ¥ ¸ðµÎ ¾ÏÀ¸·Î ³ª¿Ô½À´Ï´Ù. ¼ö¼úÀ» ÇÏ¿´½À´Ï´Ù.

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ÃÖÁ¾ º´¸®°á°úÀÔ´Ï´Ù. Multiple synchrounous cancer°¡ ¾Æ´Ï¶ó Å« ÇϳªÀÇ ¾ÏÀÌ¿´½À´Ï´Ù. ±íÀÌ´Â Á¶±âÀ§¾Ï¿¡ ÇØ´çÇÏ¿´´Âµ¥ ¸²ÇÁÀý ÀüÀÌ´Â ÇöÀúÇÏ¿´½À´Ï´Ù. Á¤ÀÇ »ó superficial spreading typeÀ̶ó°í ÇÒ ¼ö ¹Û¿¡ ¾øÁö¸¸ »ó´çÈ÷ aggressiveÇÑ °Í °°½À´Ï´Ù. 3¹øÀº ¹®·Ð 9¹ø (celiac) node±îÁö ÀüÀÌ°¡ ÀÖ¾ú½À´Ï´Ù. EB virus (-), c-erbB-2 (-)

Stomach, subtotal gastrectomy:
. Early gastric carcinoma
1. Location : middle third, Center at body and lesser curvature
2. Gross type : EGC type IIc
3. Histologic type : tubular adenocarcinoma, poorly (solid) differentiated with signet ring cell component (20%)
4. Histologic type by Lauren : mixed
5. Size : 9x5 cm
6. Depth of invasion : invades submucosa (sm1) (pT1b)
7. Resection margin: free from carcinoma, safety margin: proximal 2.5 cm, distal 5.5 cm
8. Lymph node metastasis : metastasis to 8 out of 57 regional lymph nodes (pN3a) (perinodal extension: absent) (8/57: "3", 6/13; "4", 0/7; "5", 0/1; "6", 0/11; "7", 0/3; "9", 2/10; "8a", 0/5; "11p", 0/2; "12a", 0/4; "4sb", 0/0; "1", 0/1)
9. Lymphatic invasion : present
10. Venous invasion : not identified
11. Perineural invasion : not identified
12. Peritoneal cytology : negative
13. AJCC stage by 7th edition: pT1b N3a


3. Anal adenocarcinoma

2015³â ȯÀÚÀÔ´Ï´Ù. Stool occult blood ¾ç¼ºÀ¸·Î ½ÃÇàÇÑ ´ëÀå³»½Ã°æ¿¡¼­ ¾Æ·¡ º´¼Ò°¡ ¹ß°ßµÇ¾ú½À´Ï´Ù. ¾î¶»°Ô »ý°¢ÇϽʴϱî?

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Á¶Á÷°Ë»ç »ó adenocarcinoma·Î ³ª¿Ô°í ¿Ü°ú¿¡¼­ transanal endoscopic resectionÀ» ÇÏ¿´½À´Ï´Ù. ºñ·Ï º´¸®¿¡¼­ ¾Æ·¡¿Í °°ÀÌ °á°ú¸¦ ÁÖ¾úÁö¸¸ º´¼ÒÀÇ À§Ä¡´Â anusÀÌ°í anal adenocarcinoma·Î º¸´Â °ÍÀÌ Å¸´çÇÒ °ÍÀ¸·Î »ý°¢ÇÕ´Ï´Ù.

Rectum, transanal rectal excision:
. Adenocarcinoma, well differentiated
1) Location: rectum
2) Gross type: polypoid
3) Size: 2.3x1.2cm
4) Depth of invasion: invades submucosa (pT1) (depth of invasion: 500§­ (0.5mm))
5) Resection margin: free from carcinoma, (safety margin: lateral, 0.2cm; deep, 0.1cm)
6) Lymphatic invasion: absent
7) Venous invasion: absent
8) Perineural invasion: absent
9) Tumor budding: no
10) Micropapillary component : no

2017³â 6¿ù 5ÀÏ ¿ù¿ä¼ÒÈ­±âÁý´ãȸ¿¡¼­ È«¼º³ë ±³¼ö´Ô²²¼­ anus¿¡ ´ëÇÏ¿© »ó¼¼È÷ ¼³¸íÇØ ÁֽŠ°Í Áß ÀϺθ¦ ¿Å±é´Ï´Ù.

Ç×¹®ÀÇ ±¸Á¶´Â º¹ÀâÇÕ´Ï´Ù.

Anal canalÀº anal verge·ÎºÎÅÍ anorectal ring±îÁöÀÇ Á¼Àº ºÎÀ§ÀÔ´Ï´Ù. Anorectal ringÀº internal sphincter¿Í puburectalis muscleÀÇ »ó´ÜºÎÀÔ´Ï´Ù. Anorectal ringÀº Á÷Àå¼öÁö°Ë»ç·Î´Â ±¸ºÐÇÒ ¼ö ÀÖÀ¸³ª ³»½Ã°æÀ¸·Î´Â ±¸ºÐÇÒ ¼ö ¾ø½À´Ï´Ù.

* Âü°í: EndoTODAY Ç×¹® Áúȯ


[References]

1) SMC Endoscopy Unit »ï¼º¼­¿ïº´¿ø ³»½Ã°æ½Ç

2) SMC Monday GI conference »ï¼º¼­¿ïº´¿ø ÀÏ¿ø³»½Ã°æ±³½Ç ¿ù¿äÁ¡½É¼ÒÈ­±âÁý´ãȸ

3) SMC Thursday endoscopy conference »ï¼º¼­¿ïº´¿ø ÀÏ¿ø³»½Ã°æ±³½Ç ¸ñ¿äÁ¡½É³»½Ã°æÁý´ãȸ

© ÀÏ¿ø³»½Ã°æ±³½Ç ¹Ù¸¥³»½Ã°æ¿¬±¸¼Ò ÀÌÁØÇà. EndoTODAY Endoscopy Learning Center. Lee Jun Haeng.