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AGC mimicking EGC¶ó´Â º´¸® °á°ú¸¦ ¹Þ¾Ò½À´Ï´Ù¸¸ ³»½Ã°æ ¼Ò°ßÀ» °ËÅäÇØ º¸¾ÒÀ» ¶§ ÃæºÐÈ÷ AGCÀÏ ¼ö ÀÖ´Â ¸ð¾çÀÎ °æ¿ìÀÔ´Ï´Ù. Borrmann type I, II, III, IV¶ó°í ¸í¸íÇÒ ¼ö ¾ø´Â AGC´Â ¸Å¿ì ´Ù¾çÇÑ Æ¯¼ºÀ» °¡Áö°í ÀÖ½À´Ï´Ù. ±× Áß¿¡¼­ ÈçÇÑ °ÍÀº (1) small EGCÀε¥ º´¼ÒÀÇ depth of invasionÀÌ ±íÀº °æ¿ìÀ̸ç (2) ÀÌó·³ AGC Borrmann type IV¶ó°í ÇÒ ¼ö ¾øÁö¸¸ º´¼Ò°¡ ³Ð°í ¹Ù´Ú¸é ÇÔ¸ôºÎÀ§°¡ ºÒ±ÔÄ¢ÇÑ °æ¿ìµµ ÀÖ½À´Ï´Ù. ÀϹÝÀûÀ¸·Î ³Ð´Ù°í AGCÀÎ°í ¾è´Ù°í EGCÀÎ °ÍÀº ¾Æ´Õ´Ï´Ù. ƯÈ÷ À¶±âÇü º´¼Ò¿¡¼­´Â ³ÐÀÌ¿Í depth of invasion°£¿¡´Â º°´Ù¸¥ °ü°è°¡ ¾ø±âµµ ÇÕ´Ï´Ù. ±×·¯³ª ÇÔ¸ôÇü º´¼Ò¿¡¼­´Â ÇÔ¸ôºÎÀÇ ±íÀÌ¿Í ÇÔ¸ôºÎÀÇ ³ÐÀÌ°¡ depth of invasion°ú ¾î´À Á¤µµ´Â °ü·ÃµÇ¾î ÀÖÀ» °ÍÀ̶ó´Â ´À³¦À» °¡Áö°í ÀÖ½À´Ï´Ù.

¹°·Ð Á¦ ´À³¦ÀÌ´Ï±î ±Ù°ÅÀڷḦ ´ë¶ó°í ÇÑ´Ù¸é ÇÒ ¸»Àº ¾ø½À´Ï´Ù. ¿ì¸®µéÀÌ ÇÏ´Â ÀÏ Áß¿¡¼­ ÀÚ·áÈ­Çϱâ´Â ¾î·ÆÁö¸¸ (=³í¹®À¸·Î ¸¸µé±â´Â ¾î·ÆÁö¸¸) practicalÇÏ°Ô´Â Å©°Ô µµ¿òÀÌ µÇ´Â °ÍµéÀÌ ¸¹´Ù°í »ý°¢ÇÕ´Ï´Ù (expert opinionÀ̶ó°í ºÎ¸£´Â °ÍµéÀÔ´Ï´Ù. Evidence-based medicine ºÐ¾ß¿¡¼­´Â °ÅÀÇ ¹«½ÃµÇ´Â °ÍÀÌÁö¸¸ Àú´Â expert opinionÀÇ ½ÅºÀÀÚÀÔ´Ï´Ù). ƯÈ÷ scienceÀÎÁö artÀÎÁö ¸íÈ®ÇÏÁö ¾ÊÀº ³»½Ã°æ ºÐ¾ß´Â ´õ¿í ±×·¯ÇÕ´Ï´Ù. µµÁ¦±³À°ÀÌ Áß¿äÇÒ ¼ö ¹Û¿¡ ¾ø½À´Ï´Ù.

Hepatocellular carcinoma, S8, simple nodular type with extranodular growth :
1. Differentiation : Edmondson grade II > III
2. Histologic type : macrotrabecular
3. Cell type : hepatic and clear
4. Tumor size : 5.5x5.5x5 cm
5. Necrosis : 40 %
6. Hemorrhage : 10 %
7. Fibrous capsule : complete
8. Tumor invasion in tumor capsule : yes
9. Microvessel invasion : peritumoral
10. Portal vein invasion : no
11. Bile duct invasion : yes
12. Serosa invasion : no
13. Intrahepatic metastasis : no
14. Multicentric occurrence : no
15. Surgical margin invasion : no (safety margin : 1 cm)

Advanced gastric carcinoma
1. Location : lower third, center at antrum and lesser curvature
2. Gross type : Borrmann type (unclassifiable) (mimicking EGC type IIc)
3. Histologic type : tubular adenocarcinoma, poorly differentiated
4. Histologic type by Lauren : intestinal
5. Size : 5.6x2.7x0.3 cm
6. Depth of invasion : extension to proper muscle (pT2a)
7. Resection margin: free from carcinoma, safety margin: proximal, 4 cm; distal, 3.2 cm
8. Lymph node metastasis : metastasis to 12 out of 41 regional lymph nodes (pN2)
9. Lymphatic invasion : present
10.Venous invasion : not identified
11.Perineural invasion : not identified

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