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60´ë ³²¼ºÀÔ´Ï´Ù. Á¶Á÷°Ë»ç¿¡¼ high grade dysplasia°¡ ³ª¿Ô½À´Ï´Ù. ¾î¶»°Ô ÇϽðڽÀ´Ï±î?
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À§¾ÏÀÇ °¡´É¼ºÀÌ 1/3 Á¤µµ µÈ´Ù°í ¼³¸íÇÏ°í Á¶±âÀ§¾Ï¿¡ ´ëÇÑ ³»½Ã°æ ÀýÁ¦¼úÀ» ÇÏ¿´½À´Ï´Ù. ½Ã¼ú °á°ú¿Í º´¸® °á°úÀÔ´Ï´Ù. Àú´Â EGC IIc + IIa ·Î º¸¾Ò´Âµ¥ º´¸®°ú¿¡¼´Â IIa + IIc ·Î º¸¾Ò½À´Ï´Ù.
[³»½Ã°æ ½Ã¼ú (À§ESD) °á°ú]
1. Pretreatment evaluation and medication
1) Sedation: yes
2) Degree of sedation: moderate
3) Antispasmodics: yes
4) Past-medical history: specific history (-)
5) Anti-thrombotic drug: no
2. Description of the lesion
1) Histological diagnosis by forceps biopsy: adenoma with HGD
2) Location: LC side of the prepyloric antrum
3) Size of the lesion: 20 x 15 mm (size of the resected specimen: 70 x 70 mm)
4) Shape: IIc+IIa
5) Ulcer: No
6) Fibrosis: No
7) Depth of invasion: mucosa (³»½Ã°æ ¼Ò°ß ÀÇ°Å)
8) Other findings: atrophic and metaplastic background mucosa (³»½Ã°æ ¼Ò°ß ÀÇ°Å)
9) Clinical staging: cT1acN0cM0
3. Procedure
Soft type transparent hood¸¦ ÀåÂøÇÑ ³»½Ã°æÀ» ÀÌ¿ëÇÏ¿´À½. Saline irrigation ÈÄ º´º¯À» ÀÚ¼¼È÷ °üÂûÇÏ¿´°í indigo carmineÀ» »ìÆ÷ÇÏ¿© º´º¯ÀÇ °æ°è¸¦ ÃÖ´ëÇÑ Á¤È®È÷ °üÂûÇÏ¿´À½. º´¼ÒÀÇ °æ°èÆÇÁ¤À» À§ÇÏ¿© NBIÀÇ µµ¿òÀ» ¹Þ¾ÒÀ½. º´¼ÒÀÇ °æ°è°¡ ºÒ¸íÈ®ÇÏ¿© ÃÖ´ëÇÑ ³Ð°Ô ½Ã¼úÇÏ¿´À½. º´¼ÒÁÖº¯¿¡ ¾à 3-5 mm °£°ÝÀ¸·Î markingÀ» ½ÃÇàÇÏ¿´°í ³»½Ã°æ ÁÖ»çħÀ» ÀÌ¿ëÇÏ¿© submucosal injection solution(normal saline + epinephrine + indigo carmine)À» marking ÇÑ ¹Ù±ùÂÊ Á¡¸·ÇÏ¿¡ ÁÖÀÔÇÏ¿© ºÎºÐÀûÀÎ submucosal fluid cushionÀ» ¸¸µé¾úÀ½. Marking ÇÑ ºÎÀ§ ¹Ù±ùÂÊ Á¡¸·À» Endo-cutting Àü·ù¸¦ Åë°ú½ÃÄÑ 360µµ circumferenctial cuttingÀ» ÇÏ¿´À½. Cutting Á÷ÈÄ ¾à°£ÀÇ ÃâÇ÷Àº Forced coagulationÀ» ÀÌ¿ëÇÏ¿© Á¶ÀýÇÏ¿´À½. º´¼ÒÀÇ Á¡¸·ÇÏ ºÎÀ§¿¡ Ãß°¡ÀûÀÎ submucosal injectionÀ» ½ÃÇàÇÑ ÈÄIT-2 knife¸¦ ÀÌ¿ëÇÏ¿© direct cutting ¹æ¹ýÀ¸·Î Á¡¸·ÇÏ ÀýÁ¦¸¦ 95% ÀÌ»ó ½ÃÇà ÈÄ snare¸¦ ÀÌ¿ëÇÏ¿© one piece complete resection ½ÃÇàÇÏ¿´À½. ½Ã¼ú µµÁß °æ¹ÌÇÑ ÃâÇ÷Àº needle knife·Î ÁöÇ÷ÇÏ¿´À¸¸ç Á» ´õ ¸¹Àº ¾çÀÇ ÃâÇ÷Àº Coagrasper¿¡ soft coagulation current¸¦ Åë°ú½ÃÄÑ ÁöÇ÷ÇÏ¿´À½. ÀýÁ¦ º´¼Ò¸¦ ¼ö°ÅÇÏ¿´À½.
4. Treatment outcome: en bloc resection (Ç¥º»Á¶°¢ÀÇ ¼ö: 1 piece)
5. Post-treatment staging assessment: cT1cN0cM0
6. Hemostatsis
1) Bleeding during the procedure: minimal
2) Bleeding after the submucosal dissection step: minimal
3) Main hemostasis method: electrocoagulation using Coagrasper
7. Immediate complication
1) Uncontrolled bleeding: no
2) Frank perforation: no
3) Other event (specify): no
8. ̵̧
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9.³»½Ã°æÀû ÀýÁ¦¼ú ÈÄ ½Ä»ç Áöħ
1) ³»½Ã°æ Ä¡·á ÈÄ ÀÏÁ¤ ±â°£ ÃâÇ÷ À§ÇèÀÌ ÀÖ½À´Ï´Ù. Ä¡·á·Î ÀÎÇÑ ±Ë¾çÀÌ ¿ÏÀüÈ÷ Ä¡À¯µÇ±â±îÁö 4-8ÁÖ°¡ ¼Ò¿äµÇ±â ¶§¹®ÀÔ´Ï´Ù. ÃâÇ÷Àº ÇǸ¦ ÅäÇϰųª Ç÷º¯(ºÓÀº »öÀÇ Ç÷º¯À̳ª Â¥Àå¸éó·³ °ËÀº»öÀÇ Èæ»öº¯), ¾îÁö·¯¿òÁõ, °©ÀÛ½º·± ¶¡ µîÀÇ Áõ¼¼·Î ³ªÅ¸³³´Ï´Ù. º°´Ù¸¥ Áõ»óÀÌ ¾ø´Ù°¡ °©ÀÚ±â Ç÷¾ÐÀÌ ¶³¾îÁö´Â ¼îÅ©·Î ³ªÅ¸³ª±âµµ ÇÕ´Ï´Ù. ½Ã¼ú ÈÄ 1-2 ÀÏ »çÀÌ¿¡ ÃâÇ÷ À§ÇèÀÌ °¡Àå ³ô½À´Ï´Ù. ½Ã¼ú ÈÄ 1 ´Þ ±îÁö´Â Áö¿¬ÃâÇ÷(delayed bleeding)ÀÌ °¡´ÉÇÕ´Ï´Ù. ¸¸¼º½ÅºÎÀüÀ̳ª °£°æº¯ ȯÀÚÀÎ °æ¿ì¿Í Ç×ÀÀ°íÁ¦³ª Ç×Ç÷¼ÒÆÇÁ¦¸¦ º¹¿ëÇϼ̴ø ȯÀÚ¿¡¼ ƯÈ÷ À§ÇèÇÕ´Ï´Ù. º´¿ø¿¡ ÀÔ¿øÇØ °è½Ã´Â µ¿¾È ³ªÅ¸³ª´Â ÃâÇ÷Àº ¾à¹°¿ä¹ý°ú ³»½Ã°æ ÁöÇ÷¼ú·Î Ä¡·áÇÕ´Ï´Ù. °£È¤ ¼ö¼úÀÌ ÇÊ¿äÇÑ °æ¿ìµµ ÀÖ½À´Ï´Ù¸¸ ¸Å¿ì µå¹® ÀÏÀÔ´Ï´Ù. µå¹°°Ô Åð¿ø ÈÄ Áý¿¡¼ ÃâÇ÷ÇÒ ¼ö ÀÖ½À´Ï´Ù. À̶§´Â °¡Àå °¡±î¿î ÀÇ·á±â°ü¿¡¼ ÀÀ±ÞÁ¶Ä¡¸¦ ¹ÞÀ¸¼Å¾ß ÇÕ´Ï´Ù.
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7) Åð¿ø ÈÄ °¡º¿î ÀÏ»ó»ýÈ°Àº °¡´ÉÇÕ´Ï´Ù. °¡º¿î ¿îµ¿(»êÃ¥, °ñÇÁ ¿¬½ÀÀå µî)Àº 2ÁÖ ÈÄ¿¡ ½ÃÀÛÇϽðí, Èûµç ¿îµ¿(Å״Ͻº, ¼ö¿µ µî)Àº 4ÁÖ ÈÄ¿¡ ½ÃÀÛÇϽʽÿÀ.
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10. Åð¿ø ÈÄ ½Ä»ç °ü·Ã 5°¡Áö Áöħ
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4) °ÅÄ£ ä¼Ò³ª µüµüÇÑ À½½ÄÀº ÁÖÀÇÇϽʽÿÀ. (´õ´ö, µµ¶óÁö, Dz°íÃß, °í»ç¸®, ±èÄ¡, °ù°¨ µî)
5) ¸Ê°Å³ª § À½½ÄÀ» ÁÖÀÇÇϽʽÿÀ. (Á£°¥, Àå¾ÆÂî·ù, ¸Å¿î ±èÄ¡·ù µî)
[º´¸® °á°ú]
Stomach, endoscopic submucosal dissection:
Early gastric carcinoma
1. Location : antrum, lesser curvature
2. Gross type : EGC type IIa+IIc
3. Histologic type : tubular adenocarcinoma, well differentiated
4. Histologic type by Lauren : intestinal
5. Size of carcinoma : (1) longest diameter, 22mm (2) vertical diameter, 15mm
6. Depth of invasion : invades mucosa (muscularis mucosa) (pT1a)
7. Resection margin : free from carcinoma(N), safety margin : distal 6 mm, proximal 12 mm, anterior 8 mm, posterior 18 mm
8. Lymphatic invasion : not identified(N)
9. Venous invasion : not identified(N)
10. Perineural invasion : not identified(N)
11. Microscopic ulcer : absent
12. Histologic heterogeneity: absent
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