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[ÀÏ¿ø³»½Ã°æ±³½Ç ¸ñ¿äÁ¡½ÉÁý´ãȸ 2016-5-12]

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1. Hiatal hernia, sliding type

±âÁØÀÌ 2cm¿¡ °¡±î½º·Î ÇØ´çÇÏ´Â Á¤µµÀÇ °æ¹ÌÇÑ hiatal hernia·Î º¸¸é ÁÁ°Ú½À´Ï´Ù.

* Âü°í: EndoTODAY Hiatal hernia


2. Borrmann type IV ù Áõ·Ê

º¸¸¸ 4Çü ÁøÇ༺ À§¾ÏÀº Á¤¸» ³õÄ¡±â ½±½À´Ï´Ù. ÀÌ·± ÇüÅ´ ´õ¿í ±×·¯ÇÕ´Ï´Ù. Ç¥¸éÀÌ À§Ã༺ À§¿°Ã³·³ º¸ÀÌ´Â °æ¿ì¿´´Âµ¥ Á¶Á÷°Ë»ç¿¡¼­ P/D adenocarcinoma°¡ ³ª¿Ô½À´Ï´Ù.

Stomach, total gastrectomy::
Advanced gastric carcinoma
1. Location : upper third, Center at body and greater curvature
2. Gross type : Borrmann type 4
3. Histologic type : tubular adenocarcinoma, poorly differentiated
4. Histologic type by Lauren : diffuse
5. Size : 12.2x8.3 cm
6. Depth of invasion : penetrates subserosal connective tissue (pT3)
7. Resection margin: free from carcinoma, safety margin: proximal 0.9 cm, distal 15.9 cm
8. Lymph node metastasis : no metastasis in 81 regional lymph nodes (pN0)
9. Lymphatic invasion : not identified
10. Venous invasion : not identified
11. Perineural invasion : present


3. Borrmann type IV µÎ¹ø° Áõ·Ê

Stomach, total gastrectomy:
Advanced gastric carcinoma
1. Location : upper third, Center at body and posterior wall
2. Gross type : Borrmann type 3
3. Histologic type : tubular adenocarcinoma, poorly differentiated
4. Histologic type by Lauren : diffuse
5. Size : 4x3 cm
6. Depth of invasion : invades serosa (pT4a)
7. Resection margin: free from carcinoma, safety margin: proximal 2 cm, distal 7.5 cm
8. Lymph node metastasis : metastasis to 6 out of 45 regional lymph nodes (pN_)
9. Lymphatic invasion : present
10. Venous invasion : not identified
11. Perineural invasion : present
12. Peritoneal cytology : negative

¾Æ·¡´Â Áý´ãȸ Áõ·Ê¸¦ ÁغñÇϽŠÀÓ»ó°­»ç ¼±»ý´Ô²²¼­ Á¤¸®ÇÑ º¸¸¸ 4Çü ÁøÇ༺ À§¾ÏÀÇ Æ¯Â¡ÀÔ´Ï´Ù.

* Âü°í: Borrmann type IV ¿¬Á¦: EndoTODAY 20130211 ºÎÅÍ EndoTODAY 20130306


4. °áÇÙ¼º Àå¿°

Cecum¿¡¼­´Â scar change°¡ ÀÖ¾ú°í ´Ù¸¥ ºÎÀ§¿¡´Â active Àå¿°ÀÌ ÀÖ¾ú´ø °æ¿ìÀÔ´Ï´Ù.

¾Æ·¡´Â Áý´ãȸ Áõ·Ê¸¦ ÁغñÇϽŠÀÓ»ó°­»ç ¼±»ý´Ô²²¼­ Á¤¸®ÇÑ °áÇÙ¼º Àå¿°ÀÇ Æ¯Â¡ÀÔ´Ï´Ù.

* Âü°í: EndoTODAY °áÇÙ¼º À§ÀåÁúȯ


5. ¾î¶² ´ëÀå¾Ï (¿ø¹ß¼º ȤÀº ÀüÀ̼º)

¿ì¿¬È÷ ½ÃÇàÇÑ CA-19-9°¡ 400U/ml Á¤µµ·Î ³ô¾Æ¼­ PET-CT ÈÄ ¼ÒÈ­±â³»°ú¸¦ ¹æ¹®ÇÑ È¯ÀÚÀÔ´Ï´Ù.

PET¿¡¼­ "Left paraaortic lymph node, left mesenteric lymph node¿¡¼­ SUVmax = 6.6À¸·Î ÃøÁ¤µÇ´Â ±¹¼Ò hypermetabolic lesionÀÌ °üÂûµÇ´Âµ¥ malignancyÀÇ metastasis °¡´É¼ºÀÌ ³ô°ÚÀ½. Hepatic flexure ºÎÀ§ colon¿¡¼­ SUVmax = 5.6À¸·Î ÃøÁ¤µÇ´Â hypermetabolic lesionÀÌ °üÂûµÇ´Âµ¥ primary malignancyÀÇ °¡´É¼ºÀÌ ÀÖ¾î colonoscopy¸¦ ±ÇÀåÇÔ" ¼Ò°ßÀ̾ú°í ´ëÀå³»½Ã°æÀ» ÇÏ¿´´Âµ¥ ´ëÀå³»½Ã°æ¿¡¼­ ÀÛÀº ¿ëÁ¾ ÀÌ¿Ü¿¡´Â ƯÀ̼ҰßÀÌ ¾ø¾ú½À´Ï´Ù.

È®ÀÎÀ» À§ÇÏ¿© explore laparotomy¸¦ ½ÃÇàÇÏ¿´½À´Ï´Ù. ¼ö¼ú ¼Ò°ßÀº "splenic flexure ÁÖº¯ÀÇ mesocolon ¿¡ poorly demarcated hard mass ÀÖ¾î, Lt.colonÀ» mobilization ÇÑ ÈÄ¿¡ Lt.colic artery¸¦ µû¶ó hard LNsÀÖ¾î dissection ½ÃÇà ÈÄ en bloc À¸·Î colonÀ» segmental resection and anastomosis ½ÃÇàÇÔ, S2 ¿¡ 2cm sized mass ÀÖ¾î margin È®º¸Çϱâ À§ÇØ Lt.lateral segmentectomy ½ÃÇàÇÔ"À¸·Î µÇ¾î ÀÖ¾ú°í ÃÖÁ¾ º´¸®´Â ¾Æ·¡¿Í °°¾Ò½À´Ï´Ù.

Colon, segmental resection:
Adenocarcinoma, moderately differentiated
1. Location: splenic flexure of colon
2. Gross type: unclassifiable
3. Size: 3x2x1.5 cm
4. Depth of invasion: 1) mainly involved pericolic adipose tissue without involvement of mucosa, 2) penetrates visceral peritoneum(pT4a)
5. Resection margin: free from carcinoma, safety margin: nearest, 2.5 cm ; opposite, 3 cm ; radial, > 5mm
6. Regional lymph node metastasis : metastasis to 11 out of 12 regional lymph nodes(pN2b)
7. Lymphatic invasion: present
8. Venous invasion: present (extramural)
9. Perineural invasion: present (++)
10. Tumor budding : negative
11. Associated findings : metastasis
12. Pathologic staging: pT4a N2b M1a (liver)

º´¸®°ú¿¡¼­´Â ´ëÀå¾Ïó·³ °á°ú¸¦ ÁÖ¼ÌÁö¸¸ Àú´Â (1) ¿ø¹ßºÎÀ§°¡ ´ëÀå¾ÏÀÌ°í °£ÀüÀÌ°¡ µ¿¹ÝµÈ °ÍÀÎÁö, (2) ¾îµð¼±°¡ unknown originÀÇ ¾ÏÀÌ °£°ú ´ëÀå¿¡ ÀüÀÌµÈ °ÍÀÎÁö È®½ÅÀÌ µéÁö ¾Ê¾Ò½À´Ï´Ù. Á¡¸·Ãþ¿¡´Â ¾ÏÀÌ ¾ø°í ÁÖ·Î pericolic adipose tissue¿¡¸¸ ¾Ï¼¼Æ÷°¡ Á¸ÀçÇÏ´Â ´ëÀå¾ÏÀ» ¸¸³­ ÀûÀÌ ¾ø±â ¶§¹®ÀÔ´Ï´Ù.

¿©ÇÏÆ° ´ëÀå¾ÏÀÌ¶ó °¡Á¤ÇÏ°í ¸»¾¸µå¸®¸é, ´ëÀå³»½Ã°æ¿¡¼­´Â Áúº´ÀÌ ¹ß°ßµÇÁö ¾Ê¾Ò½À´Ï´Ù. CA-19-9 »ó½ÂÀ¸·Î ÀÎÇÏ¿© explo lapa¸¦ ÅëÇÏ¿© ´ëÀå¾ÏÀÌ Áø´ÜµÈ µå¹® °æ¿ì¿´½À´Ï´Ù. ´ëÀå³»½Ã°æ¿¡´Â Ç×»ó blind area°¡ ÀÖ´Ù´Â °ÍÀ» ¸í½ÉÇսôÙ.

Àú´Â °Ç°­°ËÁø¿¡ CA 19-9°¡ Æ÷ÇԵǴ °ÍÀ» ¹Ý´ëÇÕ´Ï´Ù. µæÀ» º¸´Â »ç¶÷Àº º°·Î ¾ø°í ¼ÕÇغ¸´Â »ç¶÷Àº ¸¹Àº °Í °°½À´Ï´Ù (°³ÀÎÀûÀÎ ´À³¦).


6. Xanthoma

Xanthoma´Â flat ÇÏ´Ù°í »ý°¢ÇÏ´Â ºÐÀÌ ¸¹Áö¸¸ ÀÌ Áõ·Êó·³ À¶±âµÈ °æ¿ìµµ ¸¹½À´Ï´Ù. ´Ù¾çÇÑ xanthomaÀÔ´Ï´Ù.

* Âü°í: ÃÖ±Ù ´ëÇÑ»óºÎÀ§Àå°üÇ︮ÄÚ¹ÚÅÍ ÇÐȸÁö¿¡ ½Ç¸° ¸®ºä°¡ ÀÖ¾î ¼Ò°³ÇÕ´Ï´Ù.


[References]

1) SMC Endoscopy Unit »ï¼º¼­¿ïº´¿ø ³»½Ã°æ½Ç

2) SMC Monday GI conference »ï¼º¼­¿ïº´¿ø ÀÏ¿ø³»½Ã°æ±³½Ç ¿ù¿äÁ¡½É¼ÒÈ­±âÁý´ãȸ

3) SMC Thursday endoscopy conference »ï¼º¼­¿ïº´¿ø ÀÏ¿ø³»½Ã°æ±³½Ç ¸ñ¿äÁ¡½É³»½Ã°æÁý´ãȸ

© EndoTODAY Endoscopy Learning Center. Jun Haeng Lee.