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[Gastric cancer 490]

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Endoscopic prediction of invasion depth is not easy. Based on the multiple converging folds with fusion, I thought it would be SM cancer. To my surprise, however, it was AGC with subserosal invasion.

Estimation of invasion depth is relatively easy for differentiated type tumors. Gastric cancer with undifferentiated-type histology is difficult to guess the exact invasion depth before surgery.


Stomach, subtotal gastrectomy:
Advanced gastric carcinoma
1. Location : middle third, Center at body and greater curvature
2. Gross type : Borrmann type 3
3. Histologic type : tubular adenocarcinoma, poorly (poorly cohesive) differentiated
4. Histologic type by Lauren : diffuse
5. Size : 2.5x2.5 cm
6. Depth of invasion : penetrates subserosal connective tissue (pT3)
7. Resection margin: free from carcinoma, safety margin: proximal 3 cm, distal 11 cm
8. Lymph node metastasis : no metastasis in 70 regional lymph nodes (pN0)
9. Lymphatic invasion : present (+++)
10. Venous invasion : not identified
11. Perineural invasion : not identified
12. Peritoneal cytology : negative
13. AJCC stage by 7th edition: pT3 N0


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