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À§ lymphoma´Â Å©°Ô MALToma, diffuse large B cell lymphoma (DLBCL, °ú°Å¿¡´Â DLBL·Î ºÒ·¶À¸³ª ÃÖ±Ù¿¡´Â ´ëºÎºÐ DLBCL·Î ºÎ¸£°í ÀÖÀ½) ¹× ±âŸ ¾ÆÇüµé·Î ³ª´ ¼ö ÀÖ½À´Ï´Ù. MALToma´Â ºñ±³Àû ÃÖ±Ù¿¡ ±â¼úµÇ¾ú°í, ±âŸ ¾ÆÇüµéÀº »ó´çÈ÷ µå¹® ÁúȯÀ̹ǷÎ, °ú°ÅºÎÅÍ À§ lymphoma¿¡ ´ëÇÑ ±â¼úÀº gastric DLBCLÀÇ ¼Ò°ß¿¡ ÁßÁ¡ÀÌ ÀÖ¾î¿Ô½À´Ï´Ù. DLBCL·Î ´ëÇ¥µÇ´Â À§ lymphomaÀÇ ÀüÅëÀûÀÎ ³»½Ã°æ ¼Ò°ßÀ» Àß ¿ä¾àÇÑ ±³°ú¼ÀÇ ÀϺÎ(Yamada et al. eds. Textbook of Gastroenterology. 2nd ed. 1995:1515)¸¦ ¿Å±â¸é ´ÙÀ½°ú °°½À´Ï´Ù.
"Gastric lymphoma can be grossly indistinguishable from adenocarcinoma, but is actually a diffusely infiltrating submucosal lesion. As such, the tumor may present as a polypoid lesion with ulcerations, but like other submucosal lesions, the overlying mucosa may traverse the mass as a characteristic bridging fold. Lymphomas do not have a predilection for any particular region of the stomach, but are more likely than other cancers to present with diffuse infiltration and enlarged rugal folds.
ÀÌ·¯ÇÑ ±â¼ú¿¡ µû¸£¸é À§¸²ÇÁÁ¾Àº adenocarcinoma¿Í ±¸ºÐÀÌ ¾î·Æ°í submucosal tumor (SMT)³ª Borrmann type IV ÁøÇ༺ À§¾ÏÀÇ Æ¯Â¡À» ¸¹ÀÌ º¸ÀÌ´Â °ÍÀ¸·Î ÀÌÇØµÉ ¼ö ÀÖ½À´Ï´Ù.
ÀϺΠ¼Ò°ßÀÌ °ãÄ¡´Â °ÍÀº »ç½ÇÀÌÁö¸¸, ÀÚ¼¼È÷ °üÂûÇغ¸¸é ÁøÇ༺À§¾Ï°ú lymphoma, ƯÈ÷ DLBCLÀº »ó´çÈ÷ ´Ù¸¥ ³»½Ã°æ ¼Ò°ßÀ» °¡Áö°í ÀÖ½À´Ï´Ù. ÀÌ È¯ÀÚ¿¡¼´Â ¿©·¯ ´Ù¾çÇÑ ¸ð½ÀÀÇ º´¼Ò°¡ µ¿½Ã¿¡ ¹ß°ßµÇ¾ú´Ù´Â Á¡ÀÌ Æ¯Â¡ÀÔ´Ï´Ù. ÁÂÃø »çÁøÀÇ »¡°£»ö È»ìÇ¥·Î Ç¥½ÃµÈ ºÎÀ§´Â Borrmann type II ÁøÇ༺À§¾Ï°ú ºñ½ÁÇÕ´Ï´Ù. ÁÂÃø »çÁøÀÇ ÆĶõ»ö È»ìÇ¥·Î Ç¥½ÃµÈ ºÎÀ§´Â SMT-like cancer¿Í ºñ½ÁÇÕ´Ï´Ù. ¿ìÃø »çÁøÀÇ »¡°£ Á¡¼±À¸·Î Ç¥½ÃÇÑ ºÎÀ§´Â µÎ °³ÀÇ Borrmann type III ÁøÇ༺À§¾Ï°ú ºñ½ÁÇÕ´Ï´Ù. ÇÑ êÖ¿¡¼ ¿©·¯ ´Ù¾çÇÑ ¸ð¾çÀÇ º´¼Ò°¡ ¹ß°ßµÇ¸é lymphomaÀÇ °¡´É¼ºÀ» ¹Ýµå½Ã °í·ÁÇØ¾ß ÇÏ°Ú½À´Ï´Ù.
ÀÌ È¯ÀÚ¿¡¼ °í·ÁµÇ¾î¾ß ÇÒ ¶Ç ´Ù¸¥ ƯÀÌÇÑ ¼Ò°ßÀº Áõ»ó¾øÀÌ °ÇÁøÀ» ÅëÇÏ¿© ¹ß°ßµÇ¾ú´Ù´Â Á¡ÀÔ´Ï´Ù. °ÇÁø¿¡¼ ¹ß°ßµÇ´Â ÁúȯÀ̶ó°í ¸ðµÎ °£´ÜÇÑ º´Àº ¾Æ´ÔÀ» ÀØÁö ¸»¾Æ¾ß ÇÏ°Ú½À´Ï´Ù.
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