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[Gastric cancer 680 - scar after biopsy]

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Á¶Á÷°Ë»ç´Â submucosal fibrosis¸¦ ¸¸µé ¼ö ÀÖ½À´Ï´Ù. À§¾Ï ¹ß°ß ÈÄ º´¿øÀ» ¿Å°Ü ³»½Ã°æ ¹× Á¶Á÷°Ë»ç ´Ù½ÃÇÏ¿© À§¾ÏÀ» º´¸®ÇÐÀûÀ¸·Î µÎ ¹ø È®ÀÎÇÑ ÈÄ ÀÇ·ÚµÈ È¯ÀÚÀÔ´Ï´Ù. ESD¸¦ ÇÏ¿´´Âµ¥ À°¾È¼Ò°ß¿¡¼­ óÀ½¿¡ ¾ø´ø fold º¯È­µµ »ý°å°í, ½ÇÁ¦·Î submucosal fibrosis°¡ ÀÖ¾î ESD ½Ã¼úÀÌ ´Ù¼Ò ¾î·Á¿üÀ¸³ª º° ¹®Á¦¾øÀÌ Á¾·áµÇ¾ú°í (ÃâÇ÷Àº ¸¹¾ÒÀ½) ÃÖÁ¾ º´¸®°á°ú´Â ÁÁ¾Ò½À´Ï´Ù.


ESD: Early gastric carcinoma
1. Location : low body, anterior wall and lesser curvature
2. Gross type : EGC type IIb+IIc
3. Histologic type : tubular adenocarcinoma, moderately differentiated
4. Histologic type by Lauren : intestinal
5. Size of carcinoma : (1) longest diameter, 6 mm (2) vertical diameter, 5 mm
6. Depth of invasion : invades mucosa (lamina propria) (pT1a)
7. Resection margin : free from carcinoma(N), safety margin : distal 16 mm, proximal 15 mm, anterior 22 mm, posterior 18 mm, deep 800 §­
8. Lymphatic invasion : not identified(N)
9. Venous invasion : not identified(N)
10. Perineural invasion : not identified(N)
11. Microscopic ulcer : absent
12. Histologic heterogeneity: absent


ù ³»½Ã°æ¿¡¼­ º´¼Ò°¡ Â÷ºÐÈ÷ Àß °üÂûµÇ¾ú°í ÁúÁÁÀº »çÁøÀÌ ³²°ÜÁ® ÀÖ´Ù¸é Ä¡·á Àü ³»½Ã°æ ¹× Á¶Á÷°Ë»ç¸¦ Àç°ËÇÒ ÇÊ¿ä´Â ¾ø´Ù°í »ý°¢ÇÕ´Ï´Ù. ½ÇÁ¦·Î ESD¸¦ À§ÇÏ¿© Àú¿¡°Ô ÀÇ·ÚµÈ È¯ÀÚÀÇ ´ëºÎºÐÀº ³»½Ã°æ Àç°Ë ¾øÀÌ ¹Ù·Î ½Ã¼úÀ» ¹Þ°í ÀÖ½À´Ï´Ù. 15³â µ¿¾È ÀÌ·¸°Ô ÇØ ¿Ô´Âµ¥ Çѹøµµ ÈÄȸÇÑ ÀûÀº ¾ø¾ú½À´Ï´Ù. ¹°·Ð ÀǷڵǾúÀ» ´ç½Ã »çÁøÀÌ ÁÁÁö ¾Ê°Å³ª º´¼ÒÀÇ Æ¯Â¡ÀÌ ¹Ì½É½À¸¸é Àç°ËÀ» ÇÕ´Ï´Ù (Àüü ȯÀÚÀÇ 10% ¹Ì¸¸).

±×·±µ¥ ÀÌ·¯ÇÑ Àü·«Àº º¸ÆíÀûÀÌÁö ¾Ê½À´Ï´Ù. ´ëºÎºÐÀÇ Àü¹®°¡µéÀº À§¾ÏÀ¸·Î ÀÇ·ÚµÈ È¯ÀÚÀÌ´õ¶óµµ ESD Àü ³»½Ã°æ Àç°ËÀ» ÇÕ´Ï´Ù. ¸¹Àº ºÐµéÀº Á¶Á÷°Ë»ç±îÁö Àç°ËÀ» ÇÏ°í ÀÖÀ¸¸ç, ¼Ò¼öÀÇ Àü¹®°¡µéÀº Á¶Á÷°Ë»ç´Â ÇÏÁö ¾Ê°í »ö¼Ò³»½Ã°æ, EUS, ȤÀº È®´ë³»½Ã°æ µîÀ» ÇÏ°í °è½Ê´Ï´Ù. Àú´Â ³»½Ã°æ Àç°ËÀ» ÇÏÁö ¾Ê°í ½Ã¼úÇÏ°í ÀÖÀ¸¹Ç·Î ´Ã ¾à°£ ºÒ¾ÈÇÏÁö¸¸, ½Ã¼ú Àü Àç°ËÇÑ´Ù°í »óȲÀÌ ´õ È®½ÇÇØÁö´Â °Íµµ ¾Æ´Ï°í, Àç°Ë °ü·ÃµÈ È¥¼±µµ ¸¹°í, ¶Ç ¿À´ÃÀÇ Áõ·Êó·³ submucosal fibrosis°¡ ¹ß»ýÇÏ¿© ½Ã¼úÀÌ ¾î·Á¿öÁö°Å³ª ºÒ°¡´ÉÇØÁö´Â °æ¿ìµµ ÀÖÀ¸¹Ç·Î Àç°ËÀÇ µæ½ÇÀº ¸íÈ®ÇÏÁö ¾Ê´Ù°í »ý°¢ÇÕ´Ï´Ù.

ÀÇ·á¿¡µµ ½Ã¼úÀÚÀÇ ¼º°ÝÀÌ ¹Ý¿µµË´Ï´Ù. ¸í¹éÇÑ °¡À̵å¶óÀÎÀÌ ÀÖ´Â °æ¿ì´Â ¿Ïº®ÇÑ Ç¥ÁØÈ­°¡ °¡´ÉÇÏÁö¸¸, °¡À̵å¶óÀÎÀÌ ¾ø´Â grey zone¿¡¼­´Â ÀÇ»çÀÇ ¼º°ÝÀÌ Áø·á¿¡ ¹Ý¿µµË´Ï´Ù. Àú´Â ´ã¹éÇÑ °ÍÀ» ÁÁ¾ÆÇÕ´Ï´Ù. ²À ÇÊ¿äÇÏÁö ¾ÊÀ¸¸é ÇÏÁö ¾Ê´Â °ÍÀÌÁö¿ä.


[References]

1) EndoTODAY ESD¸¦ À§ÇØ ÀÇ·ÚµÈ È¯ÀÚ¿¡¼­ Àç°ËÀ» ÇÒ °ÍÀΰ¡?

© ÀÏ¿ø³»½Ã°æ±³½Ç ¹Ù¸¥³»½Ã°æ¿¬±¸¼Ò ÀÌÁØÇà. EndoTODAY Endoscopy Learning Center. Lee Jun Haeng. (2018-9-30)