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[Gastric cancer 646 - Deep SM invasion and multiple lymph node metastasis]

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Selection of ESD candidate can be tricky. Depressed lesion with converging folds can be deep submucosal cancer. Sometimes, initial endoscopy image may not enouth to make firm conclusion. Repeating EGC is sometimes necessary.

À§¾ÏÀ¸·Î ÀÇ·ÚµÈ È¯ÀÚÀÔ´Ï´Ù. ³»½Ã°æ °á°úÁö¿¡´Â "1.5cm sized irregular mucosal lesion at proximal body (PW). MarginÀÌ ¸íÈ®ÇÏÁö ¾Ê°í bed´Â ¾à°£ dirty ÇÏ°í hard ÇÏ°í ¹Ì¹ÌÇÑ spontaneous bleedingÀÌ º¸ÀÓ"À¸·Î ¾º¿© ÀÖ¾ú°í Á¶Á÷°Ë»ç °á°úÁö´Â M/D adenocarcinoma¿´½À´Ï´Ù.

ÇÔ¸ôÇü º´¼ÒÀÌ°í ¶Ñ·ÇÇÑ fold convergency°¡ ÀÖ°í marginÀÌ ¿Ã¶ó¿Í ÀÖÀ¸¸ç ¾à°£ µÎÅùÇغ¸¿© Áï½Ã ¼ö¼úÀ» ±ÇÇÏ¿´½À´Ï´Ù.

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Total gastrectomy: Early gastric carcinoma
1. Location : [1] upper third, Center at cardia (Siewert II), and lesser curvature
2. Gross type : EGC type IIc
3. Histologic type : tubular adenocarcinoma, moderately differentiated
4. Histologic type by Lauren : mixed
5. Size : 5x4.6 cm
6. Depth of invasion : invades submucosa (sm3) (pT1b)
7. Resection margin: free from carcinoma, safety margin: proximal 2.5 cm, distal 12.8 cm
8. Lymph node metastasis : metastasis to 7 out of 104 regional lymph nodes (pN3a) (perinodal extension: present) (7/104: "2", 3/8; "3", 1/11; "4", 1/19; "5", 0/5; "6", 0/8; "7", 0/11; "9", 1/8; "8a", 0/3; "11p", 0/0; "12a", 0/6; "4sb", 0/9; "1", 0/11; "16a-2", 1/1; "10", 0/3; "4a", 0/1)
9. Lymphatic invasion : present
10. Venous invasion : not identified
11. Perineural invasion : not identified
12. Peritoneal cytology : negative
13. AJCC stage by 8th edition: pT1b N3a

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© ÀÏ¿ø³»½Ã°æ±³½Ç ¹Ù¸¥³»½Ã°æ¿¬±¸¼Ò ÀÌÁØÇà. EndoTODAY Endoscopy Learning Center. Lee Jun Haeng. (2018-7-24)