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[Gastric cancer 663 - Neuroendocrine carcinoma with hepatic metastasis]
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Neuroendocrine carcinoma can develop and grow very rapidly.
In this case, regular endoscopic followup was done after endoscopic resection of early gastric cancer arising from adenoma. He suddenly developed upper abdominal discomfort. Endoscopy showed a large ulcerative lesion in the antrum, and the pathology was neuroendocrine carcinoma. There were multiple metastases in the liver. Previous endoscopic images (8 months ago) were reviewed, but there was no evidence of gastric cancer recurrence or neuroendocrine neoplasms. Only subtle erosions were suspicious.
NEUROENDOCRINE CARCINOMA, POORLY DIFFERENTIATED (grade 3)
. Mitosis: 12 / 10 HPF
. Synaptophysin: Positive in some tumor cells
. Chromogranin: Negative
. CD56: Diffuse strong positive
. Ki-67: Positive in about 30% of tumor cells
© 일원내시경교실 바른내시경연구소 이준행. EndoTODAY Endoscopy Learning Center. Lee Jun Haeng. (2018-8-16)