[Gastric cancer 809. Mantle cell lymphoma of the stomach]
Parasite | Eso | Sto | Cancer | ESD
[Gastric cancer 809. Mantle cell lymphoma of the stomach]
001 | 101 | 201 | 301 | 401 | 501 | 601 | 701 | 801 | 901 | 1000
The histological diagnosis of gastric MALToma and gastric mantle cell lymphoma may be confusing. The most distinguishing feature is cyclin-D1 positive in mantel cell lymphoma and cyclin-D1 negastive in MALT lymphoma. However, immonohistochemical staining of cylin-D1 is not routinely done for typical MALToma cases.
In about 15 years ago, we experience a case with mantle cell lymphoma, which was considered as MALToma of the stomach. Based on the gastric forcep biopsy result, H. pylori eradication therapy was done under the impression of gastric MALToma.
A few months later, the patient suddenly developed ileocecal intussusception and surgical resection was done.
To our surprise, the final pathology was cyclin-D1 positive mantle cell lymphoma.
When we reviewed the original gastric specimen, it was concluded that the initial correct diagnosis was gastric mantle cell lymphoma. Cyclin-D1 immunohistochemistry is still very useful for cases with uncertain pathologic diagnosis.
© 일원내시경교실 바른내시경연구소 이준행. EndoTODAY Endoscopy Learning Center. Lee Jun Haeng. (2019-11-14)
